P119 The effects of the COVID-19 lockdown on severe asthma in patients taking biologic therapy and air pollution

Khan, MA; Rajendram, Rajkumar; Al-Jahdali, H.H.; Alhamadi, MA; Alabdulaali, SK; Al-Ghamdi, BA

doi:10.1136/thorax-2020-btsabstracts.264

Cited by 2 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Evidence about hospital admission in adult asthmatics during lockdown is scarce. In Massachusetts there was a 64% decline in asthma admission of both children and adults [ 11 ] and in Japan [ 25 ] a 54% reduction in adult admissions, whereas reports from Italy [ 26 ] and Saudi Arabia [ 27 ] from patients with mainly severe asthma suggest good control with no increase in exacerbations frequency. Namely, a survey in Italy, a neighboring country to Greece, with similar climate, reported a low number of asthma exacerbations and good disease control during the Quarantine, as specialists advocated drug adherence and furthermore, home isolation may have reduced late winter/spring pollen exposure [ 26 ].…”

Section: Discussionmentioning

confidence: 99%

“…There is evidence about good overall asthma control without increase in the frequency of community treated exacerbations [ 26 , 27 , 28 ]. Concerning COPD exacerbations, there is a single center UK based study that exhibits an increase in community treated exacerbations at the beginning of the lockdown, with concomitant decrease in hospitalizations.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of COVID-19-Related Lockdown οn Hospital Admissions for Asthma and COPD Exacerbations: Associations with Air Pollution and Patient Characteristics

Sigala

Giannakas

Giannakoulis

et al. 2021

JPM

View full text Add to dashboard Cite

We conducted a retrospective observational study to assess the hospitalization rates for acute exacerbations of asthma and COPD (chronic obstructive pulmonary disease) during the first imposed lockdown in Athens, Greece. Patient characteristics and the concentration of eight air pollutants [namely, NO (nitrogen monoxide), NO2 (nitrogen dioxide), CO (carbon monoxide), PM2.5 (particulate matter 2.5), PM10 (particulate matter 10), O3 (ozone), SO2 (sulfur dioxide) and benzene] were considered. A total of 153 consecutive hospital admissions were studied. Reduced admissions occurred in the Lockdown period compared to the Pre-lockdown 2020 (p < 0.001) or the Control 2019 (p = 0.007) period. Furthermore, the concentration of 6/8 air pollutants positively correlated with weekly hospital admissions in 2020 and significantly decreased during the lockdown. Finally, admitted patients for asthma exacerbation during the lockdown were younger (p = 0.046) and less frequently presented respiratory failure (p = 0.038), whereas patients with COPD presented higher blood eosinophil percentage (p = 0.017) and count (p = 0.012). Overall, admissions for asthma and COPD exacerbations decreased during the lockdown. This might be partially explained by reduction of air pollution during this period while medical care avoidance behavior, especially among elderly patients cannot be excluded. Our findings aid in understanding the untold impact of the pandemic on diseases beyond COVID-19, focusing on patients with obstructive diseases.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Effect of COVID-19-Related Lockdown οn Hospital Admissions for Asthma and COPD Exacerbations: Associations with Air Pollution and Patient Characteristics

Sigala

Giannakas

Giannakoulis

et al. 2021

JPM

View full text Add to dashboard Cite

show abstract

“…There is some evidence about asthma that suggest good overall control with no increase in the frequency of community treated exacerbations (26)(27)(28). About COPD, there is a single center UK based study that exhibits an increase in community treated exacerbations at the begging of lockdown, with concomitant decrease in hospitalizations.…”

Section: Discussionmentioning

confidence: 99%

Effect of COVID-19-related Lockdown οn Hospital Admissions for Asthma and COPD Exacerbations: Associations with Air Pollution and Patient Characteristics

Sigala¹,

Giannakas²,

Giannakoulis³

et al. 2021

Preprint

View full text Add to dashboard Cite

We conducted a retrospective observational study to assess the hospitalization rates for acute exacerbations of asthma and/or COPD during the first imposed lockdown in Athens, Greece. Patient characteristics and the concentration of eight air pollutants (namely, CO, NO, NO2, O3 PM2.5, PM10, SO2 and benzene) were considered. A total of 153 consecutive hospital admissions were studied. Reduced admissions occurred in the lockdown period when compared to the Pre-lockdown 2020 (p&lt;0.001) or the Control 2019 (p=0.007) period. Furthermore, the concentration of 6/8 air pollutants positively correlated with weekly hospital admissions in 2020 and significantly decreased during the lockdown. Finally, admitted patients for asthma exacerbation during the lockdown were younger (p=0.046) and less frequently presented respiratory failure (p=0.038), whereas patients with COPD presented higher blood eosinophil percentage (p=0.017) and count (p=0.012). Overall, admissions for asthma and COPD exacerbations decreased during the lockdown. This might partially explained by reduction of air pollution during this period while medical care avoidance behavior, especially among elderly patients cannot be excluded. Our findings aid in understanding the untold impact of the pandemic on diseases beyond COVID-19, focusing on patients with obstructive diseases..

show abstract

P119 The effects of the COVID-19 lockdown on severe asthma in patients taking biologic therapy and air pollution

Cited by 2 publications

References 0 publications

Effect of COVID-19-Related Lockdown οn Hospital Admissions for Asthma and COPD Exacerbations: Associations with Air Pollution and Patient Characteristics

Effect of COVID-19-Related Lockdown οn Hospital Admissions for Asthma and COPD Exacerbations: Associations with Air Pollution and Patient Characteristics

Effect of COVID-19-related Lockdown οn Hospital Admissions for Asthma and COPD Exacerbations: Associations with Air Pollution and Patient Characteristics

Contact Info

Product

Resources

About