P125 The peripheral neuropathy in asymptomatic patients with vitamin B12 deficiency

Boylu, Ece; Şenol, Mehmet Güney; Saraçoğlu, Mehmet

doi:10.1016/s1388-2457(08)60396-x

Cited by 1 publication

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“…They also reported that electrophysiological findings may be normal in asymptomatic patients without neuropathic symptoms, while it was also reported that pathological findings can be found in nerve conduction studies. 15,16 As a result of polyneuropathy, superficial and deep sensory losses in proprioceptive and vibration senses can be seen. This sensory loss may cause deterioration in balance and postural stability and consequently increase the risk of falling.…”

Section: Discussionmentioning

confidence: 99%

“…ÖZET Amaç: Asemptomatik B12 vitamini eksikliği olan hastalarda postural stabilite ve düşme riskini değerlendirmeyi amaçladık. Gereç ve Yöntemler: Çalışmaya üst ekstremiteye ait şikayetleri nedeniyle fiziksel tıp ve rehabilitasyon polikliniğine başvuran hastalardan, B12 vitamini eksikliği (<200 pq/dl) olan ve elektromiyografi sonuçlarına göre nöropatisi bulunmayan 50 hasta (34 kadın, 16 erkek; ortalama yaş±SS: 35±12 yıl; yaş aralığı: 18-58 yıl) dahil edildi. Ayrıca yaş ve cinsiyetleri benzer olan 49 sağlıklı kontrol bireyi (35 kadın, 14 erkek; ortalama yaş±SS: 34±8 yıl; yaş aralığı: 24-60 yıl) alındı.…”

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Postural Stability and Risk of Fall in Vitamin B12 Deficiency

Kul¹,

Bilge²,

Uzkeser³

et al. 2020

J PMR Sci

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We aimed to evaluate postural stability and risk of fall in patients with asymptomatic vitamin B12 deficiency. Material and Methods: Fifty patients (34 women, 16 men; mean age ± SD: 35±12 years; age range: 18-58 years) who applied to physical medicine and rehabilitation outpatient clinic due to complaints of upper extremity with vitamin B12 deficiency (<200 pq/dl) and without neuropathy according to electromyography results were included in the study. In addition, a total of 49 healthy control subjects (mean age 34±8 years; range 24 to 60 years), 35 females and 14 males with similar age and sex, were included. Gender, age, body mass index (BMI) values and fall history in the last year of the participants were recorded. Fear of falling was evaluated with the Falls Efficacy Scale International (FES-I). With the Tetrax interactive balance system, which is an objective computerized method, posturographic evaluation of the participants was made. In the evaluation of postural stability; the stability index (SI) based on the displacement of the center of gravity and weight distribution index (WDI) on 4 platforms were used. On the other hand, the fall risk results were determined as a numerical value between 0-100. Postural stability and fall risk analyses were evaluated according to the results of the posturographic examination. Results: In the patient group, fall history, FES-I score, some SI values and the risk of falling were significantly higher (p<0.05). There was no significant relationship between FES-I and gender, age, BMI, and history of fall, while there was a weak negative correlation between some SI values and fall risk (r=0.03 and p<0.05). However, there was no correlation between the severity of vitamin B12 deficiency and the risk of falling. Conclusions: It was found that postural stability is affected, and the risk of fall is increased in patients with asymptomatic vitamin B12 deficiency. This increase in risk of fall was found to be associated with vitamin B12 deficiency but not with the severity of the deficiency.

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Section: Discussionmentioning

confidence: 99%

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