Contemporary medical industry standards in healthcare settings mandate that an instrument is not placed in contact with the mucosal tissue of two different patients without intervening sterilization of the instrument. Yet it is a routine practice, especially in school settings, for different students to play the same wind musical instruments without sterilization even though these instruments may have been in contact with the mucosal tissue of multiple persons. Multiple laboratory-based microbiological experiments designed to investigate issues concerning bacterial existence and survival on musical wind instruments were conducted. Bacterial growth and survival on musical wind instruments were demonstrated, establishing the viability of pathogenic bacteria on musical wind instruments and their mouthpieces. These findings suggest that standard infection control procedures ought to be applied to the practice of sharing musical wind instruments to reduce the risk of spreading infections between users.