P1438impact of Hospitalization on Body Composition of Dialysis Patients

Abstract

Background and Aims Patients with CKD are at higher risk of hospitalization (hosp) and this event is a known marker of prognosis. In this study we aim to describe hospitalizations in LatinAmerica and the impact on body composition as measured by multifrequency bioimpedance. Method All hospitalizations from Fresenius Medical Care clinical database (EuCliD®) registered in dialysis patients from Argentina, Brasil, Chile, Colombia, Ecuador and Perú during calendar year 2018 were included into the analysis. For each hospitalization we reviewed main reason (ICD10 code), duration and outcome (discharge or death). Body composition was measured using multifrequency bioimpedance (BMC®). On patients with BCM data available in the 30 days prior to hospitalization and before 15 days after discharge values pre and post hospitalization were recorded (BCM data, lab data, treatment data). Pre and post data were compared using Student t test for paired samples. All values expressed as mean ± standard deviation (SD). Results During all calendar year 2018, a total of 23,347 hospitalizations from 44,228 patients were recorded. Mean age was 61.4 ± 16.1 / Male 56.4% / diabetes 38.7%. Accounting for time at risk, hosp rate was 0.74 hosp/pt-year at risk. Mean stay at hospital was 10.9 ± 14.4 days (7.6 days/pt-yr). 35.24% of patients suffer at least one hosp during the year. Reasons for hospitalization are indicated in table 1: Conclusion: Hospitalization in dialysis patients is a frequent event. It has a significant impact on Hb, Ca, P and Albumin levels. Although net patient's weight is significantly reduced, real decrease in muscular and fat mass may be masked by increase in excess water (overhydration) as shown in our results. An early BCM measurement and dry weight adjustment after discharge may be a helpful tool for patient management optimization.