P15.01: Risk assessment of pre‐eclampsia according to FMF model in local practice

Abstract

Objectives:The study aim was to assess the early pre-eclampsia (<34 weeks) risk distribution, computed for 1290 patients with single pregnancy at 11-13 + 6 gestational weeks, as well as the prediction algorithm efficiency for a threshold value of 1 in 100. Methods: The pre-eclampsia risk was calculated using the competitive risk model developed by the Fetal Medicine Foundation, starting from an a priori risk based on history and maternal characteristics. Basal risk was adjusted according to maternal blood pressure, pulse rate index of uterine arteries and protein A associated with pregnancy, resulting a final risk. We used a program developed in Matlab. Evolution of pregnancy, respectively the development of pre-eclampsia and was evaluated retrospectively after birth. Results: 101 (9.7%) cases had a risk greater than 1 in 100 to develop early pre-eclampsia. The detection rate of pre-eclampsia was 84%. Conclusions: The model developed by FMF for prediction of pre-eclampsia is a robust protocol, with 10% of patients eligible for Aspirin prophylaxis. The detection rate is similar to that in model development studies, but is already influenced by Aspirin prophylaxis in the high-risk group. P15.02Three-dimensional power Doppler ultrasound evaluation of the orbital vascularities in pre-eclampsia