“…In most cases, it begins by confirming the presence of fever in-hospital. A minimal workup includes a complete history and physical examination, including drug history, complete blood count with differential (CBCD), blood film, routine blood chemistry, urinalysis and microscopy, blood and urine cultures, anti-nuclear antibodies (ANA), rheumatoid factor (RF), HIV antibodies, cytomegalovirus (CMV), IgM antibodies, heterophile antibody test (if consistent with mononeucleosis-like syndrome), Q fever serology (if exposure to risk factors exists), chest X-ray and hepatitis serology (if liver enzymes are elevated) 11. The role of different nuclear medicine studies (e.g., labeled leukocytes, gallium, indium and technetium scans) was emphasized in these patients, especially in ruling out inflammatory conditions 14–21…”