P2.04-037 Solitary Fibrous Tumor of the Pleura Associated with Severe Hypoglicemia: The Doege-Potter Syndrome

Ventura, Luigi; Gnetti, Letizia; Braggio, Cesare; Carbognani, Paolo; Rusca, Michele; Silini, Enrico Maria; Ampollini, Luca

doi:10.1016/j.jtho.2016.11.1417

Cited by 1 publication

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“…The most frequent paraneoplastic syndromes mentioned in the Some others consider that the incidence of malign PSFT is much higher, with the percentile reaching 43% of the cases [21]. Even though, it is accepted that approximately 78-88% of the cases represent benign PSFT and only 12% to 22% represent malignant cases [22]. In this context, there were some major criteria of malignancy put in place: mitotic index higher than 4/10 HPF, intratumoral necrosis or haemorrhage, pleomorphic cells, and the presence of metastasis; a minor criterion is represented by a size larger than 10 cm [13].…”

Section: Discussionmentioning

confidence: 99%

Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients

et al. 2020

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Introduction: The purpose of this paper is to study the type, the clinical presentation, and the best diagnostic methods for pleural solitary fibrous tumors (PSFTs), as well as to evaluate which is the most appropriate treatment, especially as PSFTs represent a rare occurrence in the thoracic pathology. Material and Method: A retrospective study was conducted on a group of 45 patients submitted to surgery between January 2015 and December 2019. In most cases, the diagnosis was established through imaging studies—thoracic computed tomography (CT) scan with or without contrast—but also using magnetic resonance imaging (MRI) or positron emission tomography (PET) scans when data from CT scans were scarce. All patients were submitted to surgery with curative intent. Results: Most patients included in this study were asymptomatic, with this pathology being more common in patients over 60 years of age, and more common in women. The occurrence of malignant PSFT in our study was 17.77% (8 cases). All cases were submitted to surgery with curative intent, with a single case developing further recurrence. In order to achieve complete resection en bloc resection of the tumor with the chest wall, resection was performed in two cases, while lower lobectomy, pneumectomy, and hemidiaphragm resection, respectively, were needed in each case. Postoperative mortality was null. Conclusion: Thoracic CT scan remains the most important imagistic investigation in diagnosing. MRI is superior to thoracic CT, especially in cases that involved the larger blood vessels within the thorax, spinal column, or diaphragm. Complete surgical resection is the gold standard in treatment of PSFT, and the prognosis in benign cases is very good.

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Section: Discussionmentioning

confidence: 99%