Introduction: Myocardial ischemia is often asymptomatic and remains a first cause of morbidity and mortality in diabetic's patients. This study aimed to determine the prevalence of Silent Myocardial Ischemia (SMI) among diabetics. Methods: It was a cross sectional and analytic study with prospective data collection from April to August 2014. We included all consent diabetes aged 18 years and over. All patients with clinical and/or electrocardiographic abnormalities suggestive of coronaropathy or those with sub maximal stress test were not included. SMI was retained when the stress test was positive according to SFC/ALFEDIAM de 2004 guidelines. Results: The stress test has been done for 108 diabetics. The mean age was 50,2±11,2 years and the sex-ratio 1,6. The diabetes was type 2 in 91,5% and controlled in 66%. These patients have another cardiovascular risk factors in 87,8%. At rest, the electrocardiogram was not normal in 54,9%. After stress test 11% of diabetics were diagnosed for SMI. The history of stroke is the only one factor associated with SMI. Conclusion: These data show that SMI was frequent among diabetic in Parakou independently of diabetes' age and the resting electrocardiogram result. SMI screening is necessary to improve the management of diabetes in this city.