P3.04-002 Reducing the Amount of Resection after Induction Photodynamic and Chemotherapy in Inoperable Non-Small Cell Lung Cancer

Abstract

Background: None of the methods of intraoperative determining the sentinel lymph nodes is used in lung cancer. We tried to evaluate the features of lymphatic flow and sentinel lymph nodes (SLN) mapping in patients with NSCLC using near-infrared (NIR) fluorescence imaging. Methods: 50 patients with NSCLC (squamous cell e 34, adenocarcinoma e 15, large cell e 1) who underwent curative resections (pneumonectomy e 19, lobectomy e 31) were prospectively divided into two groups e with preoperative chemotherapy (CT+S group, 15 patients) and without (S group, 35 patients). Immediately after entering the pleural cavity 2 ml of indocyanin green (ICG) solution as an NIR fluorescent lymphatic tracer was injected in 3-4 points around the tumor. Lymphatic flow and SLN were real-time identified by fluorescence imaging system intraoperatively every 15 minutes after injection and postoperatively ex vivo. Ipsilateral hilar and mediastinal lymphadenectomy was done.