2017
DOI: 10.1016/j.jalz.2017.06.1598
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[P3–382]: NEURAL EVIDENCE FOR DEFECTIVE TOP‐DOWN CONTROL OF VISUAL PROCESSING IN PARKINSON's AND ALZHEIMER's DISEASE

Abstract: Introduction:We used a functional MRI paradigm involving conventional vs. unconventional views of objects to assess bottom-up vs. top-down visual processing in Parkinson's disease (PD) with normal cognition, PD with mild cognitive impairment (MCI), and MCI due to Alzheimer's disease (AD) as compared to healthy controls. We particularly aimed at determining whether the task discriminated between PD with and without MCI and between two MCI groups due to distinct pathologies (AD and PD). Methods: 116 right-handed… Show more

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