P300 deficits in adults with attention deficit hyperactivity disorder: a meta-analysis

Abstract

To our knowledge, this is the first meta-analysis of P3 characteristics in adults with ADHD. It reveals a significantly decreased P3 amplitude during target detection. Our result that the reduction in P3 amplitude increases with age is interpreted in a neurodevelopmental context.

How does reactivity to frustrative non-reward increase risk for externalizing symptoms?

“…Average waveforms were examined at the midline electrodes Fz, Cz, and Pz and are illustrated in Figure 1. Consistent with previous studies (see Szuromi, Czobor, Komlosi, & Bitter, 2011 for review) amplitude appeared maximal at the Pz site in the time window associated with P3b. The average response time for the entire sample was 509 ms ( SD = 55 ms).…”

Neurophysiological correlates of delinquent behaviour in adult subjects with ADHD

“…In a visual Go/Nogo task, Prox et al (2007) compared the ERPs of adult ADHD patients and controls and found a tendentially decreased P300 at parietal electrode sites and a significantly enhanced subsequent slow wave in the time window from 600 to 800 in the frontal cortex in the ADHD group relative to controls. Similar results were found by a metaanalysis conducted by Szuromi et al (2010) that showed a significantly reduced P300 amplitude related to target detection in adult ADHD subjects compared to controls. Furthermore, Barry et al (2009) reported topographic differences between an AD/HD group and controls in the P300 to visual non-targets.…”

Deficient interference control during working memory updating in adults with ADHD: An event-related potential study

“…Regular P300 amplitudes are in contrast with the data from other studies (Szuromi et al, 2011;Woltering et al, 2013). However, most studies used Go/No-Go tasks (e.g., Wiersema et al, 2006) to measure response inhibition and are therefore difficult to compare.…”