2018
DOI: 10.1093/ecco-jcc/jjx180.514
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P387 Infliximab therapeutic drug monitoring test validated for measuring CT-P13 and SB2 biosimilars

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“…Several enzyme-linked immunosorbent assay (ELISA) methods are available to allow for easy and efficient quantification of infliximab serum levels and adjustment of dose during TDM [41]. Studies have shown that commercially available assays used in patients receiving reference infliximab can also be used with confidence to monitor drug levels in patients treated with the infliximab biosimilars CT-P13 or SB2 [41][42][43][44]. Assays such as the Promonitor-ANTI-IFX kit can also be used to monitor ADAs in patients receiving reference infliximab, CT-P13 or SB2 [42].…”
Section: Therapeutic Drug Monitoring and Immunogenicitymentioning
confidence: 99%
“…Several enzyme-linked immunosorbent assay (ELISA) methods are available to allow for easy and efficient quantification of infliximab serum levels and adjustment of dose during TDM [41]. Studies have shown that commercially available assays used in patients receiving reference infliximab can also be used with confidence to monitor drug levels in patients treated with the infliximab biosimilars CT-P13 or SB2 [41][42][43][44]. Assays such as the Promonitor-ANTI-IFX kit can also be used to monitor ADAs in patients receiving reference infliximab, CT-P13 or SB2 [42].…”
Section: Therapeutic Drug Monitoring and Immunogenicitymentioning
confidence: 99%