P38Prenatal diagnosis of severe hypotonia and polihydramnius in a fetus with mitochondrial disorder

Abstract

Introduction The diagnosis of polihydramnius is ultrasound and can be measure with a various test but finally the result is the increment of the amnioticus liquid. It is secundary from a differents pathological situations but severe hypotonia is a rare cause. The hypotonia is the result of a heterogeneous group of conditions including severe hypoxia, neuromuscular disorder, deposit disease, chromosomal, and mitochondrial pathology. Case report A 30‐year‐old woman in the 40th week of gestation came to us referring a decrease in foetal movements during the last 24 h. The pregnancy curse had been normal. The foetal heart rate variability was pathological and the ultrasound study showed a decrease in respiratory movements, foetal movements and foetal tone with a abnormal amniotic liquid volume. The foetus was delivered by urgency caesarean section. A 3160‐g male was born, Apgar 6/8, pH 7.32. The newborn was taken to nciu and the neonatal outcome was unfavourable. The newborn had a severe hypotonia, hyporeflexia, the eec was pathological. Finally the newborn died.