P39.05: A study to determine the veracity of the ultrasonographic measurements of the thymus during fetal development

Abstract

myxo-fibroblastic proliferation. There was focal chorangiosis with intervening normal placental mesenchyme. The fetal chorionic plate vessels were massively dilated, tortuous and congested. There was a 3-vessel umbilical cord with furcated marginal cord insertion. Immunohistochemical studies of the abnormal myxoid villi showed minimal staining for smooth muscle actin and positive p57 KIP2 protein staining. This is only the third case of PMD with normal fetus where the p57 KIP2 protein staining was used in the diagnosis. The p57 KIP2 gene is paternally imprinted and maternally expressed. The presence of this protein indicates a functional maternal allele. This case supports the utility of p57 KIP2 protein staining in distinguishing this disorder from molar pregnancy. In our case elevated free beta-hCG level was detected in the first trimester before placental abnormalities were visualized on ultrasound. P39.05 A study to determine the veracity of the ultrasonographic measurements of the thymus during fetal development

Fetal thymus size in uncomplicated twin and singleton pregnancies

“…Fetal thymic measurements were obtained in duplicate by the same observer, allowing for a 5‐min interval between examinations. Intra‐ and interobserver reproducibility of fetal thymic measurements at our institution have been previously reported9, 23. Clinical information was retrieved from maternal and neonatal medical records by one of the investigators (P.P.…”

Comparison of measurements of the transverse diameter and perimeter of the fetal thymus obtained by magnetic resonance and ultrasound imaging

“…The calipers or trace function of the US machine were then placed at the interfaces between the thymus and the lungs. The accuracy of US fetal thymic measurements has been reported (7, 15, 16).…”