P4‐123: Educating the Public on Dementia: A School‐based Approach

Abstract

High Risk and Low Average/poor Memory class were at an elevated risk of developing incident dementia (HR ¼ 13.6, 95%CI ¼ 5.9 -31.2 and HR ¼ 5.8, 95%CI ¼ 2.6 -12.8) and incident AD (HR ¼ 11.1, 95%CI ¼ 4.7 -25.9, and HR ¼ 5.0, 95%CI ¼ 2.2 -11.2) in the first four years from baseline assessment, while participants in the Dysexecutive Function class were at an elevated risk for incident all-cause dementia and incident AD after four years of follow-up (HR ¼ 6.0, 95%CI ¼ 2.5 -14.3, and HR ¼ 7.1, 95%CI ¼ 2.7 -18.4). Results in the Elite class were not applicable in the first 4 years since there were no cases and, after 4 years results were not significant (there were only 5 cases in total). Conclusions: This study highlights the clinical applicability of the association between a patient's cognitive profile and future risk of all-cause dementia and AD. This area of research may lead to personalized risk profiles.