P46.07 Afatinib-Related Pneumonitis in Metastatic EGFR-Positive NSCLC

Andarini, Sita; Desianti, Ginanjar Arum; Hanafi, Arif Riswahyudi; Masniari, L.; Hafiz, Maida; Kusumaningtiyas, N.; Djajusman, M.; Gultom, Ferry Pergamus

doi:10.1016/j.jtho.2021.08.493

Journal of Thoracic Oncology

2021

DOI: 10.1016/j.jtho.2021.08.493

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P46.07 Afatinib-Related Pneumonitis in Metastatic EGFR-Positive NSCLC

Sita Andarini

Ginanjar Arum Desianti

Arif Riswahyudi Hanafi³

et al.

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Afatinib

2021

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Bilateral pneumonitis: case reportA 69-year-old woman developed bilateral pneumonitis during treatment with afatinib for metastatic EGFR-positive lung adenocarcinoma.The woman, who had metastatic EGFR-positive lung adenocarcinoma T3N3M1 brain, received afatinib 40mg [route not stated]. She improved; however, following two months of treatment, she reported cough and shortness of breath. Chest high-resolution (HR) CT showed bilateral pneumonitis. Based on the finding, a diagnosis of bilateral pneumonitis associated with afatinib was confirmed [duration of treatment to reaction onset not stated].The woman was treated with pulse-dose unspecified steroid after inclusion of infection and heart failure; however, her condition worsened, and she died with respiratory failure.

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Afatinib

2021

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P46.07 Afatinib-Related Pneumonitis in Metastatic EGFR-Positive NSCLC

Cited by 1 publication

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