P506 Steven‐Johnson syndrome seen in a HIV positive pregnant patient: a case report

Sulayman, Hajaratu Umar; Wanoyi, I.; Ramadan, A.

doi:10.1016/s0020-7292(09)61996-2

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2020

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“…Aetiologic agents implicated in Stevens Johnson syndrome include drugs, infections, malignancy related and idiopathic (2,4,5) . There are increasing reports of Steven Johnson syndrome among HIV positive pregnant women with nevirapine being implicated in the aetiology (6,7) . We present a case report highlighting pitfalls in the prescription of nevirapine, the morbidity of this condition and the potential for the underreporting of such occurrences.…”

Section: Introductionmentioning

confidence: 99%

Nevirapine Associated Stevens Johnson Syndrome in an HIV Positive Pregnant Woman- A Case for Pharmacovigilance.

Spo

Ma³

2020

ijmsci

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This is a case report of a 41 year old multipara with human immunodeficiency virus (HIV) infection with an interesting history. She was initially commenced on a regimen of antiretroviral which included nevirapine in her non pregnant state. A change of drugs to replace nevirapine with efavirenz was instituted when skin rash was noticed. Unfortunately, she was recommenced on nevirapine when she became pregnant at 15 weeks gestation and developed symptoms of Stevens Johnson syndrome necessitating admission and treatment following which she made a full recovery. The presentation of this case highlights the importance of pharmacovigilance and health education to patients about adverse drug reactions.

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Section: Introductionmentioning

confidence: 99%