P51 Facteurs de risque du diabète gestationnel à propos de 100 cas

Damoune, I.; Ouahabi, H. El; Ajdi, F.

doi:10.1016/s1262-3636(14)72345-6

Cited by 3 publications

(4 citation statements)

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“…Furthermore, the data from this study did not show any significant association of the obstetric variables examined with GD. This result disagrees with a previous study on 100 cases of Moroccan women [ 37 ], reporting that obstetric history was the most predominant risk factor for GD in addition to heredity of diabetes and obesity.…”

Section: Discussioncontrasting

confidence: 99%

Prevalence of gestational diabetes and associated risk factors in the population of Safi Province in Morocco

Chamlal¹,

Mbarki²,

Ayachi³

et al. 2020

Pan Afr Med J

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Introduction the association of diabetes with pregnancy is a frequent gestational situation that constitutes a real public health problem with prevalence and risk factors varying according to the population type. The present study aims to determine the prevalence of gestational diabetes (GD) and associated risk factors (socio-demographic characteristics, medical and obstetric history) in pregnant women from the Moroccan province of Safi. Methods this cross-sectional, descriptive and analytical study was conducted during the period from October 2018 to February 2019, on 208 pregnant women, attending the antenatal consultation services of four health centers equally distributed between urban and rural areas of Safi Province in Morocco. The data on blood glucose levels and the risk factors for gestational diabetes generally described in the literature were collected. The statistical Chi-square test and the logistic regression were used to check the association between gestational diabetes and the risk factors. Results the mean age of the pregnant women sample was 28.9 ± 6.8 years and the prevalence of GD was 24.5%. Using multivariate logistic regression, the most significantly associated risk factors were the diabetic inheritance of a primary relative (OR=2.616 [95% CI: 1.281-5.341]; p=0.008) and the high education level (OR=2.301 [95% CI: 1.123-4.716] p=0.023). Conclusion the results show that gestational diabetes is a frequent pathology among the study population. The data revealed also that the diabetes inheritance (primary relative) and the high level of education are the main risk factors of this pathology in the surveyed pregnant women in the study province.

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Section: Discussioncontrasting

confidence: 99%

Prevalence of gestational diabetes and associated risk factors in the population of Safi Province in Morocco

Chamlal¹,

Mbarki²,

Ayachi³

et al. 2020

Pan Afr Med J

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“…6.2%, p>0.05). In Africa, the few studies carried out have reported a prevalence ranging from 5% to 17% [6][7][8]. In France, the prevalence of gestational diabetes ranges from 2% to 6% [1,9].…”

Section: Discussionmentioning

confidence: 99%

“…The "HAPO" international study, which included nearly 24,000 women, made the following findings. Out of the patients diagnosed according to the criteria of the International Association of Diabetes and Pregnancy Study Groups (IADPSG), 55% had an abnormal level of fasting glucose, 55% had an abnormal level of blood glucose at 1 h and 38% had an abnormal level of blood glucose at 2 h [7]. In our study, we used the fasting glucose method to screen 100% of gestational diabetes cases in Group A.…”

Section: Strategies Of Gestational Diabetes Screeningmentioning

confidence: 97%

Randomized Study Comparing Two Gestational Diabetes Screening Strategies in a Reference Maternity Hospital in Southern Benin

Ogoudjobi¹,

Lokossou²,

Tognifode³

et al. 2018

Clinics Mother Child Health

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Objective: The objective of this work is to compare two gestational diabetes screening strategies. Patients and methods: We conducted a comparative randomized study that screened gestational diabetes on pregnant women who are between 24 th and 28 th weeks of amenorrhea. We conducted the trials either by measuring fasting glucose values or by a glucose tolerance test performed two hours after oral loading of 75 g glucose (WHO test). The study involved 580 pregnant women (290 for each type of trial) who came for antenatal appointment at the reference maternity hospital in Porto-Novo (Benin) between February 2 nd , 2015 and January 31 st , 2017. Results: We detected 26 cases (9%) of gestational diabetes by the "fasting glucose value measurement method" as compared to the 18 cases (6.2%) detected by the WHO test, leading to a p-value of 0.209. The two types of test were equally relevant: Sensitivity (59.09% vs. 40.91%), specificity (50.75% vs. 49.25%), positive predictive value (8.97% vs. 6.21%), and predictive value negative (93.79% vs. 91.03%). All pregnant women tested "negative" between their 24 th and their 28 th weeks of amenorrhea, were tested again during the 32 nd week of amenorrhea, using the WHO test method and no new case of gestational diabetes was detected. Conclusion: Fasting glucose value measurement method can be an alternative method for gestational diabetes screening in a population where the WHO test is not available.

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“…Studies carried out in Africa have reported prevalences ranging from 5% to 17% [31,32]. The frequency of gestational diabetes varies by country, population studied and diagnostic criteria according to International Diabetes Federation 2013 [33].…”

Section: Discussionmentioning

confidence: 99%

Predictive Value of Immunological Parameters in the Risk of Gestational Diabetes Mellitus: A Pilot Study

Fagninou

Nekoua

Fiogbe

et al. 2020

Preprint

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Background : Immunological and biochemical parameters are gaining more and more importance in the prognosis of diabetes and its complications. Here we assessed the predictive power of immunological parameters correlated with biochemical ones in gestational diabetes mellitus (GDM). Material and Methods : 217 pregnant women were screened for GDM between the 2 nd and the 3 rd trimester of gestation, based on IAGDP methods in this cross-sectional descriptive study. Immunological and biochemical parameters were determined using appropriate methods. Receiver operating characteristics (ROC) curve analyses were conducted to assess the optimal cutoff and value of immunological to biochemical parameter ratios for predicting GDM. Results : 11.90% of pregnant women were diagnosed GDM positive. Serum glucose levels, total cholesterol, LDL-cholesterol, triglycerides and total proteins were significantly increased while HDL-cholesterol decreased in women with GDM compared to controls. The levels of glycosylated hemoglobin and creatinine, as well as transaminase (AST and ALT) activities did not significantly differ between GDM and pregnant controls. Total leucocytes (white blood cell), lymphocyte and platelet numbers were significantly higher in women with GDM than in pregnant controls. We also found that the lymphocyte:HDL-C, monocyte:HDL-C and granulocyte:HDL-C ratios were significantly higher in women with GDM than in pregnant controls ( p = 0.001; p = 0.009 and p = 0.004 respectively). Women with a lymphocyte:HDL-C ratio greater than 3.66 had a 4-fold increased risk of developing GDM than those with lower ratios (odds ratio 4.00; 95% CI: 1.094 – 14.630; p =0.041). Conclusion : The lymphocyte:HDL-C, monocyte:HDL-C and granulocyte:HDL-C ratios may represent valuable makers, and the lymphocyte:HDL-C ratio in particular may have strong predictive power for GDM. This ratio can be easily assessed in patients.

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P51 Facteurs de risque du diabète gestationnel à propos de 100 cas

Cited by 3 publications

References 0 publications

Prevalence of gestational diabetes and associated risk factors in the population of Safi Province in Morocco

Prevalence of gestational diabetes and associated risk factors in the population of Safi Province in Morocco

Randomized Study Comparing Two Gestational Diabetes Screening Strategies in a Reference Maternity Hospital in Southern Benin

Predictive Value of Immunological Parameters in the Risk of Gestational Diabetes Mellitus: A Pilot Study

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