The Endocrine Society's 93rd Annual Meeting &Amp; Expo, June 4–7, 2011 - Boston 2011
DOI: 10.1210/endo-meetings.2011.part1.p2.p1-39
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P53 and CTNNB1 Mutations Reveal Different Patterns between Pediatric and Adult Adrenocortical Tumors

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Cited by 2 publications
(3 citation statements)
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“…The patient characteristics ( Table 2 , Supplementary Materials Table S1a or Table S1b ) were described in 37 publications regarding the Brazilian population [ 2 , 17 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 ] and in 57 manuscripts regarding the patients in other countries [ 1 , 3 , 4 , 7 , 9 , 13 , 17 , 56 , 57 , 58 , 59 , 60 , 61 , 62 ,…”
Section: Resultsmentioning
confidence: 99%
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“…The patient characteristics ( Table 2 , Supplementary Materials Table S1a or Table S1b ) were described in 37 publications regarding the Brazilian population [ 2 , 17 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 ] and in 57 manuscripts regarding the patients in other countries [ 1 , 3 , 4 , 7 , 9 , 13 , 17 , 56 , 57 , 58 , 59 , 60 , 61 , 62 ,…”
Section: Resultsmentioning
confidence: 99%
“…The initial staging was reported for 2238 patients in 43 publications [ 2 , 3 , 9 , 13 , 22 , 26 , 29 , 30 , 32 , 33 , 36 , 37 , 38 , 39 , 42 , 44 , 45 , 46 , 47 , 48 , 50 , 51 , 53 , 54 , 56 , 59 , 62 , 70 , 71 , 76 , 77 , 80 , 81 , 82 , 93 , 94 , 95 , 96 , 98 , 99 , 101 , 106 ]. The median number of patients in each cohort was 44.…”
Section: Resultsmentioning
confidence: 99%
“…Alterações da via Wnt/β-catenina parecem estar associadas a pior prognóstico em tumores adrenocorticais de adultos (63). Recentemente, dados do nosso laboratório demonstraram mutações do gene CTNNB1 em 6% dos TAC pediátricos, todas envolvendo sítios de fosforilação e degradação da β-catenina (64), em contraponto com a presença de mutações em 36% a 55% dos TAC de adultos, predominantemente em TAC não secretores (63,65). Um achado interessante do nosso estudo é que todos os tumores apresentando mutação no gene CTNNB1 também carreavam a mutação P53 p.R337H.…”
Section: Bases Moleculares Dos Tumores Adrenocorticaisunclassified