P545 Praziquantel in prevention of complicated echinococcosis relapses

Dautovic, Slavica; Koluder, Nada; Ferhatovic, M.; Mostarac, N.; Kapisazovic, S.; Tanovic, H.; Mesic, Amira; Gojak, Refet

doi:10.1016/s0924-8579(07)70388-6

Cited by 2 publications

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“…However, this country is being recognized as endemic for CE that is a large public health problem (Obradovic et al, 2006;Guska et al, 2007). After the war (1992)(1993)(1994)(1995), an increase in human surgical incidence accrued, especially in cities that were under the siege during that period (Dautovic et al, 2007).…”

Section: Bosnia and Herzegovinamentioning

confidence: 99%

Echinococcosis/hydatidosis: A severe threat in Mediterranean countries

Dakkak

2010

Veterinary Parasitology

180

132

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Section: Bosnia and Herzegovinamentioning

confidence: 99%

Echinococcosis/hydatidosis: A severe threat in Mediterranean countries

Dakkak

2010

Veterinary Parasitology

180

132

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“…To date, there has been very little information on CE in Bosnia and Herzegovina, with a few limited studies reporting sero-/prevalence of infection in humans and domestic animals or clinical case reports [13][14][15][16]. According to these studies, CE is recognized as the most important zoonotic disease in the country, with a prevalence ranging from 20% to 81% in cattle and sheep [16].…”

Section: Introductionmentioning

confidence: 99%

Genetic diversity of Echinococcus granulosus sensu lato from animals and humans in Bosnia and Herzegovina

et al. 2022

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Background Cystic echinococcosis (CE) is recognized as one of the most prevalent zoonotic diseases in Bosnia and Herzegovina. However, no systemic investigation of the genetic diversity of Echinococcus granulosus sensu lato circulating among animals and humans in the country has been performed to date. Methods In this preliminary study, we analysed one cyst each from 36 sheep, 27 cattle, 27 pigs, 11 wild boars and 16 human patients for amplification and partial sequencing of the adenosine triphosphate 6 (atp6) and cytochrome c oxidase 1 (cox1) genes. The host species, fertility rate and organ cyst location were recorded for each subject involved in the study. Results Overall, the atp6 gene was successfully amplified and sequenced from 110 samples, while 96 of the PCRs for cox1 were positive. Three zoonotic genotypes of E. granulosus sensu stricto (G1 and G3) and Echinococcus canadensis (G7) were identified in our isolates based on analyses of the atp6 gene. These genotypes were represented by 11 different genetic variants (haplotypes), six of which were identified for the first time in the present study. Conclusions This study demonstrates, for the first time, that CE in Bosnia and Herzegovina is predominantly caused by E. granulosus sensu stricto and E. canadensis clusters, which exhibited a lower genetic diversity compared to isolates from other European countries. Further molecular studies employing other mitochondrial and nuclear genes are required to better understand the transmission cycles of E. granulosus sensu stricto among intermediate and definitive hosts in the country. Graphical Abstract

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P545 Praziquantel in prevention of complicated echinococcosis relapses

Cited by 2 publications

References 0 publications

Echinococcosis/hydatidosis: A severe threat in Mediterranean countries

Echinococcosis/hydatidosis: A severe threat in Mediterranean countries

Genetic diversity of Echinococcus granulosus sensu lato from animals and humans in Bosnia and Herzegovina

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