P727 Quality of life and disease activity in children and adolescents with inflammatory bowel disease

Aloi, Marina; Carloni, Emilia; Palmacci, Francesca; Distante, M; Catassi, Giulia N.; D’Arcangelo, Giulia; Cucchiara, Salvatore

doi:10.1093/ecco-jcc/jjy222.851

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“…Clinical manifestations of IBD include abdominal pain, diarrhoea, fever, haematochezia and perianal abscesses. In addition, the course of IBD is usually lengthy and can be accompanied by a variety of systemic diseases that compromise the physical and mental health of patients and impose tremendous economic burdens on patients and the medical system.…”

Section: Introductionmentioning

confidence: 99%

Increased risks of dental caries and periodontal disease in Chinese patients with inflammatory bowel disease

Zhang

Gao

Zhou

et al. 2020

International Dental Journal

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Objectives: Inflammatory bowel disease (IBD) may be associated with oral diseases, but few relevant studies have been reported in China. This study aimed to compare the prevalence, severity and extent of dental caries and periodontal disease in Chinese IBD patients and healthy controls. Materials and methods: In this cross-sectional study, questionnaires and oral examinations were completed for 389 IBD patients [265 with Crohn's disease (CD) and 124 with ulcerative colitis (UC)] and 265 healthy controls based on the established criteria of the World Health Organization. Tobit regression, multiple linear regression and logistic regression were performed to analyse the data. Results: After adjusting for confounders, the decayed, missing and filled surfaces indices were significantly increased in the CD and UC patients compared with those in the controls (P < 0.001). Patients with CD [odds ratio (OR) = 4.27, 95% confidence interval (95% CI): 2.63-6.95, P < 0.001] and UC (OR = 2.21, 95% CI: 1.24-3.94, P = 0.007) had significantly higher risks of dental caries than controls. Significantly higher percentages of sites with probing pocket depth ≥ 5 mm and clinical attachment loss ≥ 4 mm were observed in CD and UC patients compared with controls (P < 0.001). A fully adjusted model revealed that CD and UC were risk indicators for periodontitis (OR = 4.46, 95% CI: 2.50-7.95, P < 0.001; OR = 4.66, 95% CI: 2.49-8.71, P < 0.001, respectively). No significant differences in dental caries and periodontal disease were observed between the CD and UC patients. Conclusions: Chinese IBD patients have a higher prevalence, severity and extent of dental caries and/or periodontal disease than controls, and require oral health education and multidisciplinary treatment.

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Section: Introductionmentioning

confidence: 99%