P729 Tigecycline usage in cancer patients with refractory pneumonia: a report on 38 cases. A single-institution study

Chemaly, R.; Hachem, Ray; Hanmod, Santosh S.; Adachi, Javier; Hogan, H.; Mulanovich, Victor E.; Kontoyiannis, Dimitrios P.; Safdar, Aqsa; Raad, Isaam; Rolston, Kenneth

doi:10.1016/s0924-8579(07)70570-8

Cited by 1 publication

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“…It has also been found to be useful in patients with severe sepsis and shock, those with community acquired pneumonia, and even in some mycobacterial infections [51,52]. Clinical experience in cancer patients is limited [53].…”

Section: Tigecyclinementioning

confidence: 99%

New antimicrobial agents for the treatment of bacterial infections in cancer patients

Rolston

2009

Hematological Oncology

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Patients with cancer develop serious bacterial infections often, especially during periods of severe and prolonged neutropenia. Antibiotic usage for the prevention and treatment of bacterial infections in these high-risk patients leads to selection pressures resulting in the emergence and spread of resistant organisms. Many organisms acquire several resistance mechanisms, making them multi-drug-resistant (MDR) (defined as resistance to three or more different classes of antibiotics). These infections are associated with increased morbidity, mortality and costs. The development of novel antimicrobial agents with activity against pathogens that have become resistant to currently available agents is one strategy for combating resistant organisms. Several novel agents have either recently been approved, or are in various stages of development and are discussed in detail. It is unlikely that these agents will have a major impact on reducing the development and spread of MDR organisms. Consequently, the judicious use of currently available agents referred to as Antimicrobial Stewardship, and the development of and adherence to appropriate Infection Control policies and procedures are vital components in the management of these high-risk patients.

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Section: Tigecyclinementioning

confidence: 99%

New antimicrobial agents for the treatment of bacterial infections in cancer patients

Rolston

2009

Hematological Oncology

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P729 Tigecycline usage in cancer patients with refractory pneumonia: a report on 38 cases. A single-institution study

Cited by 1 publication

References 0 publications

New antimicrobial agents for the treatment of bacterial infections in cancer patients

New antimicrobial agents for the treatment of bacterial infections in cancer patients

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