Aloe vera (Aloe barbadensis) an herb is widely used in Ayurvedic, Homoeopathic and Allopathic streams for its marvelous medicinal properties. This plant is one of the richest natural sources of health for mammals including human beings. The chemistry of the plant has revealed the presence of more than 200 different biologically active substances, which include antimicrobial, antibacterial, antifungal, antiviral, activities of the nonvolatile constituents of the leaf gel. Aloe species are widely distributed in the African and the eastern European continents, and are spread almost throughout the world. The genus Aloe has more than 400 species but few, such as A. vera, Aloe ferox, and Aloe arborescens, are globally used for trade. Many biological properties associated with Aloe species are contributed by inner gel of the leaves. anti diabetic, anti-infl ammatory, peptic ulcers, antitumor, anticancer Properties, activity effects on the Immune System, adverse reactions, Laxative effects, wound healing, antiseptic, vitamins, minerals, enzymes, amino acids, stress, sugars. It is known to help slow down the appearance of wrinkles and actively repair the damaged skin cells that cause the visible signs of aging. Aloe is a powerful detoxifi er, antiseptic and tonic for the nervous system. Aloe vera gel contains a large range of vitamins even vitamin B12, Vitamin A, contains B-Group vitamins, Vitamin C, Vitamin E and folic acid. Aloe vera gel contains important ingredients including 19 of the 20 amino acids needed by the human body and seven of the eight essential ones that just cannot be made. The plant leaves and inner gel contains numerous help it has potential to cure sunburns and minor cuts, and even skin cancer and acts as also acts as extremely powerful laxative. Various parts of the plant have different effects on the body. The present review is an attempt to highlight the proven research related botanical and pharmacological medicinal properties of Aloe vera.