PA03.16. Role of herbal immunomodulators in Paediatric practice

Manohar, INilesh; Kumari, O. Sita; Kumar, Abhimanyu

doi:10.4103/0257-7941.123913

Cited by 1 publication

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Numerous finding has supported that it acts as anti-inflammatory, antispasmodic and also showed immunomodulatory properties. Its chemical profile contains various significant active molecules like Piperine, Piperine, pellitorine, caryophyllene, etc., as major chemical constituents 27,[89][90][91] . The extract of P. longum was significantly involved in improving the immune system through activating macrophages in vitro study.…”

Section: Pippali[piper Longum]mentioning

confidence: 99%

“…), and phagocytic index (P.I.) in mice [90][91] . Numerous studies have proven that SARS-CoV-2 mainly damages the immune system and induces oxidative stress, cause damage to airway epithelial cells.…”

Section: Pippali[piper Longum]mentioning

confidence: 99%

“…Additionally, an increased cytokine level causes damages to tissue damage of the lungs, kidney, and heart and leads to severe complications like respiratory failure, etc 91 . Other findings supported that the extract of P. longum as a supplement acts as anti-viral activity against different viruses, reduced stress, anti-inflammatory effect, and reduced the level of cytokines 89 .…”

Section: Pippali[piper Longum]mentioning

confidence: 99%

See 2 more Smart Citations

Repurposing of the Herbals as Immune-Boosters in the Prevention and Management of COVID-19: A Review

Kumari¹,

Venaik²,

Hasibuzzaman³

et al. 2021

J Pure Appl Microbiol

View full text Add to dashboard Cite

Coronavirus disease (COVID) is highly contagious, and negligence of it causes high morbidity and mortality globally. The highly infectious viral disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was abbreviated as COVID-19 (Coronavirus disease 2019) by World Health Organization first time on February 11, 2020, and later on, WHO declared COVID-19 as a global pandemic on 11/3/2020. Epidemiological studies demonstrated that the SARS CoV-2 infects the overall population, irrespective of age, gender, or ethnic variation, but it was observed in clinical studies that older and compromised immunity population is much more prone to COVID-19. SARS-CoV-2 majorly spread through aeration route in droplet form on sneezing and coughing, or by contact when touching eyes, nose or mouth with the infected hands or any other organs, resulting from mild to severe range of SARS-CoV-2 infection. This literature-based review was done by searching the relevant SCI and SCOPUS papers on the pandemic, SARS-CoV-2 and COVID-19, herbal formulation, and Ayurveda from the databases, Academia, Google Scholar, PubMed, and ResearchGate. The present review attempts to recognize the therapeutic strategies to combat COVID-19 because of the current human risk. Indian system of medicine, including herbals, has immense potential in treating and managing various viral infections and provides evidence to utilize Ayurvedic medication to improve immunity. Cumulative research findings suggest that Ayurvedic formulations and herbal immunomodulators (Tino sporacordifolia, Withania somnifera, Crocus sativus, Zafran, Allium sativum, Zingiber officinale, Albizia lebbek, Terminalia chebula, Piper longum, Mangifera indica, Ocimum sanctum, Centella asiatica ) are promising in the treatment of outrageous viral infections without exerting adverse effects. Considering the ancient wisdom of knowledge, the herbal formulations would compel healthcare policymakers to endorse Ayurveda formulations to control the COVID-19 pandemic significantly.

show abstract

Section: Pippali[piper Longum]mentioning

confidence: 99%

Section: Pippali[piper Longum]mentioning

confidence: 99%