Survey report on predicting positive Coronary Artery Disease from symptoms and evolving a diagnostic package for the 128 sliced computed tomography for a multispecialty hospital by using six sigma methodologies. Materials and methods Dynamic 128-slice Computed Tomography Scan was performed in patients admitted to the radiology department among October 2013 to January 2014. This paper deals with the data based decision making process by implementing Zero defect quality, Six Sigma methodologies. The presentation makes an attempt to study the "Existing process of numerous data generation" towards zero defect quality and make the Computed Tomography Scan diagnostic intelligent technology aware among the common man in bringing awareness on "Early Detection, Prediction and Prevention". To continuously upgrade the technology for an early diagnosis and to render excellent quality treatment to the patients.