“…In terms of advantages, the vein is comparatively large in caliber (and hence can comfortably accommodate multiple leads), usually readily accessible through venipuncture, and anatomically close to the preferred pulse generator site in the infraclavicular space. In terms of disadvantages, the vein is anatomically close to many vital structures at risk of accidental damage during venipuncture, and the medial subclavicular musculotendinous complex capable of damaging leads through compression and flexion 3,4,57 . To avoid subclavian crush, the axillary vein is preferable to the subclavian vein as the point of venous entry, but the subclavian vein is bigger in caliber, more constant in position anatomically, and generally easier to puncture.…”