Pacinian neurofibroma: A rare neurogenic tumor

Congenital cutaneous solitary mixed hamartoma: An unusual case containing eccrine, neural, and lipomatous components

“…The onion bulb formation is noncapsulated, often poorly or incompletely differentiated, and devoid of a central nerve fiber. 7 Pacinian corpuscle-like structures are often embedded in the myxoid stroma, which stains positively with alcian blue. 7 In our case, however, the structures within the lower compartment of the nodule were composed of encapsulated corpuscles with eosinophilic central cores surrounded by 13 to 25 concentric lamellae of attenuated cells.…”

“… 7 Pacinian corpuscle-like structures are often embedded in the myxoid stroma, which stains positively with alcian blue. 7 In our case, however, the structures within the lower compartment of the nodule were composed of encapsulated corpuscles with eosinophilic central cores surrounded by 13 to 25 concentric lamellae of attenuated cells. The inner core and surrounding lamellae were immunopositive for S-100 protein, and the outer perineurial cells stained positive for epithelial membrane antigen.…”