Pain as the only symptom of cervical artery dissection

Arnold, Marcel

doi:10.1136/jnnp.2006.094359

Cited by 142 publications

(111 citation statements)

References 22 publications

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“…This agrees with previous studies [4][5][6][7][8]. In ICAD patients, pain was significantly more frequent in the anterior part of the head, compared to VAD, where pain occurred in the nuchal and/or occipital region.…”

Section: Discussionsupporting

confidence: 92%

“…Inclusion criteria were: extracranial SCAD diagnosed by magnetic resonance imaging (MRI), magnetic resonance angiography, computed tomography angiography (CTA) or conventional angiography. Extracranial SCAD was based on classical angiographic signs such a irregular stenosis ("string sign"), double lumen or intimal flap, presence of mural hematoma on cervical MRI or CTA within the C1 segment of the internal carotid artery (ICA) or within the V1 to V3 segments of the vertebral artery (VA) [2,6]. Dissections were considered as spontaneous when they occurred spontaneously or in association with non-traumatic precipitating activity or minor trauma [1].…”

Section: Methodsmentioning

confidence: 99%

“…The localization, the characteristics of dissection-related headache and the presence of symptoms that could mimick a migraine attack were recorded. Pain intensity in the SCAD episode was quantified by a numerical rating scale (NRS), graded in unit increments from zero (no pain) to 10 (worst pain) [6].…”

Section: Methodsmentioning

confidence: 99%

“…Headache, facial or neck pain are common presenting symptoms of SCAD, although mechanisms underlying dissection-related pain remains incompletely understood [4][5][6][7][8]. The relationship between previous migraine and painful SCAD was investigated in only two studies with opposite findings and therefore it is still a matter of controversy [4,5].…”

Section: Introductionmentioning

confidence: 99%

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Primary headaches and painful spontaneous cervical artery dissection

et al. 2007

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The relation between primary headaches (PH) and pain related to spontaneous cervical artery dissection (SCAD) is still unclear, as well as the progress of PH after dissection. To investigate this relation, the characteristics of pain related to SCAD and changes in PH patterns after SCAD, we evaluated 54 consecutive patients. Thirty-five (65%) had previous PH. Painful SCAD occurred in 39 (72%). Frontal and parietal localizations were significantly associated with internal carotid artery dissection (p=0.013 and p=0.010, respectively), whereas occipital and nuchal pain, with vertebral artery dissection (p=0.047 and p<0.001, respectively). Previous PH did not influence the presence of pain at SCAD onset. Twenty-six (74%) patients with PH reported improvement in PH pattern after a mean follow-up of 32 months. These results suggest that mechanisms underlying PH do not modulate dissectionrelated pain. Disruption of perivascular afferents may be involved in improvement of PH patterns after SCAD.

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Section: Discussionsupporting

confidence: 92%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Primary headaches and painful spontaneous cervical artery dissection

et al. 2007

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“…Patients may present with isolated local manifestations, ischemic signs or both [3]. However, the most appropriate end point in follow-up studies remains unclear: several studies used functional outcome, measured with the modified Rankin Scale score (mRS) or the recurrence rate.…”

Section: Introductionmentioning

confidence: 99%