2007
DOI: 10.1016/j.jns.2006.12.012
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Pain as the presenting symptom of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)

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Cited by 44 publications
(28 citation statements)
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“…Although having a length-dependent, sensory painful neuropathy pattern in the initial period of the disease, the presence of an important proximal weakness in the lower limbs in the absence of a significant distal weakness in the upper limbs, and the non-uniform demyelinating pattern observed on NCS suggested this patient had a non length-dependent demyelinating neuropathy, compatible to CIDP 4 , that may occasionally be heralded by pain 5 . CSF is highly abnormal in patients with CIDP when several punctures are carried out, but one normal examination does not rule out this disease As there was no improvement with steroid treatment, a sural nerve biopsy was carried out, revealing an amyloid infiltrate.…”
Section: Discussionmentioning
confidence: 84%
“…Although having a length-dependent, sensory painful neuropathy pattern in the initial period of the disease, the presence of an important proximal weakness in the lower limbs in the absence of a significant distal weakness in the upper limbs, and the non-uniform demyelinating pattern observed on NCS suggested this patient had a non length-dependent demyelinating neuropathy, compatible to CIDP 4 , that may occasionally be heralded by pain 5 . CSF is highly abnormal in patients with CIDP when several punctures are carried out, but one normal examination does not rule out this disease As there was no improvement with steroid treatment, a sural nerve biopsy was carried out, revealing an amyloid infiltrate.…”
Section: Discussionmentioning
confidence: 84%
“…Although pain is typically regarded as a secondary sign of CIDP, Boukhris et al [21] described the characteristics of 5 patients in whom pain was the main cause of referral and the most prominent symptom. Patients presented initially with pain in the lower limbs associated with modest motor impairment (1 case), distal paresthesia (4 cases), cramps (1 case) and fatigue (2 cases).…”
Section: Pain In Immune-mediated Neuropathiesmentioning
confidence: 99%
“…As an example of the role of chemokine signaling in chronic pain one might consider PNS and CNS inflammatory demyelinating diseases such as GuillainBarré syndrome, Charcot-Marie-Tooth disease types 1 and 4, and multiple sclerosis, which are frequently accompanied by a neuropathic pain syndrome (76,77). Epidemiological studies suggest that chronic pain syndromes afflict 50-80% of patients with multiple sclerosis and 70-90% of individuals with Guillain-Barré syndrome (78).…”
Section: Chemokines and Their Receptors In Acute And Chronic Painmentioning
confidence: 99%