Pain, depressive symptoms, and health‐related quality of life among survivors of pediatric hematopoietic stem cell transplant

Klages, Kimberly L; Chardon, Marie L; Drake, Sarah; Myers, Kasiani C.; Morrison, Caroline F.; Pai, Ahna L. H.

doi:10.1002/pbc.29846

Cited by 3 publications

(1 citation statement)

References 42 publications

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“…There is research indicating a significant positive correlation between changes in pain intensity and subsequent depressive symptoms. [12,13] For elderly people, moderate or severe pain significantly affects their physical and mental health. [14][15][16] Musculoskeletal pain, myofascial pain, neuropathic pain, and visceral pain are the main types of pain that affect depression in patients.…”

Section: Introductionmentioning

confidence: 99%

Association between pain intensity and depressive status in patients with hip fracture: An observational study

Jiang,

Sheng,

et al. 2024

Medicine

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Identifying depression symptoms in patients with hip fractures and studying the relationship between depression and pain intensity and pain location in hip fracture patients is of great significance for disease recovery in hip fracture patients. This cohort study analyzed 5 wave data from the China Health and Retirement Longitudinal Study in 2011, 2013, 2015, 2018, and 2020, focusing on 1222 patients with hip fractures. The study utilized the CESD-10 Depression Scale to assess depressive symptoms in hip fracture patients and conducted analyses to explore the relationship between depression symptoms, pain, and pain intensity, including binary logistic regression and examination of interaction terms between pain variables and pain intensity in key body parts. Depression symptoms are strongly associated with pain intensity in hip fracture patients, particularly in key body areas. Severe pain significantly increases the risk of depressive symptoms. Moreover, absence of pain in other key body parts is linked to depressive symptoms. Multivariate analysis reveals that higher education levels, marriage, urban residence, and self-rated good health serve as protective factors against depression, while diabetes and heart disease pose significant risks for depressive symptoms in hip fracture patients. Hip fracture pain can induce discomfort and trigger depressive symptoms, showing varied trajectories among patients. Pain intensity predicts the course of depressive symptoms, emphasizing the importance of tailored pain management strategies including medication, physical therapy, and nonpharmacological interventions. Personalized rehabilitation and mental health plans should be designed based on individual patient needs and differences.

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Section: Introductionmentioning

confidence: 99%

Association between pain intensity and depressive status in patients with hip fracture: An observational study

Jiang,

Sheng,

et al. 2024

Medicine

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Long-Term Complications after Allogeneic Hematopoietic Stem Cell Transplantation with Treosulfan- or Busulfan-Based Conditioning in Pediatric Patients with Acute Leukemia or Myelodysplastic Syndrome: Results of an Associazione Italiana Ematologia Oncologia Pediatrica Retrospective Study

Saglio,

Pagliara,

Zecca

et al. 2024

Transplantation and Cellular Therapy

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Depression in transplantation

Zimbrean¹

2022

Current Opinion in Organ Transplantation

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Purpose of reviewTo review and summarize the literature published between 1 January 2020 and 30 June 2022, on the prevalence, risk factors and impact of depression in transplant population. Recent findingsDepression is common in transplantation candidates and recipients, with a prevalence up to 85.8% in kidney recipients. Multiple studies have indicated after transplantation depression correlates with increased mortality and with higher healthcare utilization. Social risk factors for posttransplant depression include financial difficulties and unemployment, while less is understood about the biological substrate of depression in this population. There is evidence that dynamic psychotherapy is effective for depression in organ transplant recipients, while cognitive behavioral therapy or supportive therapy did not lead to improvement of depression in transplant recipients. For living organ donors, the rates of depression are similar to the general population, with financial factors and the clinical status of the recipient playing a significant role. SummaryDepression is a common finding in transplant population. More research is needed to understand the biological substrate and risk factors and to develop effective treatment interventions.

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Pain, depressive symptoms, and health‐related quality of life among survivors of pediatric hematopoietic stem cell transplant

Cited by 3 publications

References 42 publications

Association between pain intensity and depressive status in patients with hip fracture: An observational study

Association between pain intensity and depressive status in patients with hip fracture: An observational study

Long-Term Complications after Allogeneic Hematopoietic Stem Cell Transplantation with Treosulfan- or Busulfan-Based Conditioning in Pediatric Patients with Acute Leukemia or Myelodysplastic Syndrome: Results of an Associazione Italiana Ematologia Oncologia Pediatrica Retrospective Study

Depression in transplantation

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