Pain in Hospitalized Pediatric Patients: How Are We Doing?

Ellis, Jacqueline; O'connor, Barbara Virley; Cappelli, Mario; Goodman, John T.; Blouin, Renee; Reid, Craig W.

doi:10.1097/00002508-200207000-00007

Cited by 73 publications

(51 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Hospitalised children regularly suffer from moderate to severe pain [1][2][3][4][5]. Sadly inadequate pain treatment shown in the 1980s and 1990s is still prevailing [6,7].…”

Section: Introductionmentioning

confidence: 99%

Analgesic Drug Prescription Patterns on Five International Paediatric Wards

et al. 2016

View full text Add to dashboard Cite

Key points• Use of analgesic and anti-inflammatory drugs was in line with local recommendations and WHO guidelines • Oral paracetamol and oral ibuprofen are the most commonly used analgesic drugs on general paediatric wards • Differences regarding dose and frequency of ibuprofen and paracetamol use were observed, indicating that safety concerns for individual drugs are perceived differently among countries BOTZENHARDT et al. 2/1 2016-09-16 ABSTRACT AimAnalgesic and anti-inflammatory drugs are frequently prescribed in paediatrics. Prescribing and dosing patterns in hospitalised children are not well known. This study explores analgesic drug utilisation on five paediatric wards and discusses its findings in comparison with WHO guidelines. MethodA sub-analysis of a prospective, multi-centre, observational cohort study was undertaken. Prescription data of children aged up to ≤18 years were collected between October 2008 and December 2009 on paediatric general medical wards in five hospitals in Australia, Germany, the United Kingdom (UK), Hong Kong (HK) and Malaysia. Analgesic drug prescriptions were analysed for prescribing patterns in terms of dosing, frequency and route of administration. Dosing data were compared with local recommendations and WHO guidelines for children. ResultsIn the study cohort 56.8% (726/1,278) of paediatric patients received at least one analgesic drug prescription (1,227 prescriptions). Median age of patients with analgesics was 2.2 years (IQR 0.8-7.3) and median number of prescriptions per patient was 1 (IQR 1-2). Most commonly prescribed drugs were oral paracetamol (45.9%, 563/1,227) and oral ibuprofen (19.9%, 244/1,227). Daily doses of paracetamol ranged from 30 mg/kg/day in Germany to 67-68 mg/kg/day in UK and HK (p<0.05). For ibuprofen, single doses ranged from 5-6 mg/kg in HK and UK to 10 mg/kg in GER and AUS (p<0.001). Opioid use prevalence was statistically different between the centres and ranged from 0% to 17.6% (p<0.001). ConclusionThis study provides a comprehensive overview of analgesic drug use of hospitalised children. Similar to primary care data, paracetamol is the most commonly used analgesic. As recommended by WHO guidelines, oral medication was favoured and opioids used in addition to paracetamol and ibuprofen. Overall drug utilisation was in line with local recommendations and WHO guidelines. Differences in use of paracetamol and ibuprofen among countries was seen indicating that safety concerns are perceived differently. More large-scale safety studies are needed. BOTZENHARDT et al.

show abstract

“…Hospitalised children regularly suffer from moderate to severe pain [1][2][3][4][5]. Sadly inadequate pain treatment shown in the 1980s and 1990s is still prevailing [6,7].…”

Section: Introductionmentioning

confidence: 99%

Analgesic Drug Prescription Patterns on Five International Paediatric Wards

et al. 2016

View full text Add to dashboard Cite

show abstract

“…However, bridging the gap between this knowledge and everyday clinical practice remains a major difficulty. [6][7][8] Implementation of pain measurement for all children who are potentially in pain, application of effective up-to-date treatments, and improved research and education on the causes, prevention, and short-term and longterm effects of pain and analgesia remain important priorities.…”

mentioning

confidence: 99%