Pain Management in Burn Patients

Nosanov, Lauren B; Brandt, Jennifer; Schneider, Daniel; Johnson, Laura S.

doi:10.1007/s40719-020-00203-9

Cited by 14 publications

(5 citation statements)

References 95 publications

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“…The oxycodone in plasma serum was only detectable in single samples, and oxycodone concentration did not exceed a few ng/mL. Their amounts could not be accountable for the pain management effects observed [38,40]. Values of oxycodone concentration providing analgesia after IV oxycodone administration are ten times higher [41].…”

Section: Discussionmentioning

confidence: 93%

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Analgesic Efficacy of Oxycodone in Postoperative Dressings after Surgical Treatment of Burn Wounds: A Randomised Controlled Trial

Kowalski,

Leppert,

Domagalska

et al. 2024

JCM

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Introduction: This study aimed to assess the analgesic efficacy of oxycodone at doses of 10 mg and 20 mg in dressings after surgery of burn wounds. Material and Methods: Twenty adult patients who underwent surgical treatment of third-degree burn wounds under general anaesthesia were included. Burn wounds were treated with dressings, to which oxycodone was added at 20 mg in Group 1 and 10 mg in Group 2. After the surgery, plasma oxycodone and noroxycodone concentrations were assayed, and pain intensity was assessed with Numerical Rating Scale (NRS). Results: In Group 1, no patient reported pain; in Group 2, four patients reported pain. The pain intensity, according to NRS, was 1–8. Plasma concentration of oxycodone in the blood serum was in the range of 1.24–3.15 ng/mL and 1.09–1.28 ng/mL in Group 1 and Group 2, respectively. Noroxycodone was not detected in the plasma. Adverse effects were not observed in any of the treated patients. Conclusions: Oxycodone in dressings provides patients with adequate and safe analgesia.

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Section: Discussionmentioning

confidence: 93%

“…Even when using systemically high opioid doses, such sound effects were not observed [7,[37][38][39]. The oxycodone in plasma serum was only detectable in single samples, and oxycodone concentration did not exceed a few ng/mL.…”

Section: Discussionmentioning

confidence: 94%

Analgesic Efficacy of Oxycodone in Postoperative Dressings after Surgical Treatment of Burn Wounds: A Randomised Controlled Trial

Kowalski,

Leppert,

Domagalska

et al. 2024

JCM

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“…This is important, since pain chronification may increase the already higher risks of burn patients in developing mental health impairments, such as acute stress disorder (ASD), post-traumatic stress disorder (PTSD), elevated stress levels, depression, and insomnia ( 6 , 67 ). Especially in times of an ongoing opioid crisis, complementary treatments to pharmacological strategies for pain management in burn patients are needed not only for procedural pain, but also for background pain ( 68 ). In a previous meta-analysis of music interventions and pain in different medical settings, Lee ( 28 ) found a statistically significant reduction in opioid intake.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Music Therapy on Perceived Pain, Mental Health, Vital Signs, and Medication Usage of Burn Patients Hospitalized in the Intensive Care Unit: A Randomized Controlled Feasibility Study Protocol

et al. 2021

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Background: Burn patients experience major physiological and psychological stressors during treatment and rehabilitation, including elevated levels of pain, anxiety, stress, or depression. Music interventions inclusive of music therapy (MT) have been shown to improve such symptoms, but rigorous clinical trials investigating specific music therapy methods in adult burn patients are scarce.Methods: This is a single center Randomized Controlled Trial (RCT) protocol with two parallel arms. Participants are 81 adult burn patients admitted to the Intensive Care Unit (ICU) of the University Hospital Fundación Santa Fe de Bogotá in Colombia. The intervention consists of a Music Assisted Relaxation (MAR) protocol, a music therapy technique composed of entrained live music combined with a guided relaxation and/or the use of imagery. The effects of the MAR will be compared to a control group (treatment as usual) over a period of maximum 2 weeks or six interventions. The primary outcome measure is perceived background pain, as measured with a Visual Analog Scale (VAS) before and after each intervention. Secondary outcomes are anxiety and depression levels; vital signs; and the use of pain medication. Additionally, some patients in the intervention group will be invited to participate in electroencephalography, electromyography, and electrocardiography recordings during the MAR.Discussion: This study protocol follows the SPIRIT guidelines for defining items of clinical trials and is the first study in Colombia to evaluate the effects of music therapy for adult burn patients. With this RCT it is hoped to gather new knowledge about the potential of music therapy to help critical care patients cope and recover from their injuries during the hospitalization in the ICU.Trial registration:www.clinicaltrials.gov, Identifier: NCT04571255.Protocol version: V1.0, May 24th 2021

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“…It is crucial to educate staff, patients, and families on burn-related pain and its harmful consequences. The educational program should address addiction and pain communication through pain scales (Nosanov et al, 2020). A personalized treatment plan considers individual opioid effectiveness and drug tolerance development (Foster, 2014).…”

Section: Treatment and Management Guidelinesmentioning

confidence: 99%

Management of Procedural Pain in Pediatric Burnt Patients: A Review

Elsadek

2024

Am. J. Med. Sci. Innov.

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Burn injuries are the sixth leading cause of mortality globally and among the top five causes of injury in pediatrics. Therefore, this study aimed to review the methods and treatments for managing procedural pain in pediatric burnt patients, focusing on alleviating burning sensations effectively. Data were gathered from various electronic databases spanning 2015 to 2024 using keywords related to pain management, burn injuries, and intervention strategies. Utilizing frameworks like SPIDER, PICO, and ROBIS, 85 articles were selected for review, elucidating interventions, pain assessment criteria, and management guidelines. The review underscores the progress in effective therapies while aiming to determine the prevalence and treatment of procedural burn pain in pediatrics. Further, it encompasses treatment criteria, protocols, pharmacological and non-pharmacological interventions, and lifestyle modifications. This indicates that effective treatment options are progressing. This review concluded personalized, multimodal pain treatment methods for enhancing the health and efficiency of patients in vulnerable situations.

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Pain Management in Burn Patients

Cited by 14 publications

References 95 publications

Analgesic Efficacy of Oxycodone in Postoperative Dressings after Surgical Treatment of Burn Wounds: A Randomised Controlled Trial

Analgesic Efficacy of Oxycodone in Postoperative Dressings after Surgical Treatment of Burn Wounds: A Randomised Controlled Trial

The Effect of Music Therapy on Perceived Pain, Mental Health, Vital Signs, and Medication Usage of Burn Patients Hospitalized in the Intensive Care Unit: A Randomized Controlled Feasibility Study Protocol

Management of Procedural Pain in Pediatric Burnt Patients: A Review

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