Pain Relief in Hospital: the More Widespread Use of Nitrous Oxide

Entonox as an analgesic agent during panretinal photocoagulation

“…14 Self administration of Entonox as an analgesic has been widely used for many years, particularly in obstetric practice 15 and by paramedics for prehospital care. 16 Entonox has a good safety record, with no serious side effects recorded for intermittent use, 14 and is rapidly cleared from the circulation by exhalation. 17 There were no adverse effects during this study.…”

Midazolam in conjunction with local anaesthesia is superior to Entonox in providing pain relief during bone marrow aspirate and trephine biopsy

“…Patients may not use the apparatus properly, either due to technique or anticipation of pain 13. Studies in obstetrics have revealed that up to 30% of the patients have inadequate pain relief when Entonox is administered to relieve labour pain 14.…”

Schmerzkonzept einer kinderchirurgischen Klinik

“…In England erfolgte 1961 erstmals die Applikation eines Gemisches aus 50% Lachgas und 50% Sauerstoff (ENTONOX®) zur Schmerzreduktion unter der Geburt [16]. Das Gasgemisch erwies sich in seiner Anwendung als sicher, zeigte eine gute analgetische und sedierende Wirkung sowie einen hohen Patientenkomfort [5].…”