Painful Tumors of the Skin

Herzberg, Arlene J.; Murphy, Gëorge F.

doi:10.1111/j.1524-4725.1993.tb00344.x

Cited by 14 publications

(3 citation statements)

References 33 publications

(46 reference statements)

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“…Nur wenige Autoren haben sich bisher mit den mög-lichen Ursachen der Schmerzhaftigkeit von bestimmten Hauttumoren auseinander gesetzt. Unter anderem wurden eine Vermehrung, Stimulation oder abnorme Konfiguration von intratumoralen Nerven angenommen, darüber hinaus auch Defekte im Lipidmetabolismus und Reaktionen auf bestimmte Neurotransmitter [3]. Auch die Möglichkeit einer Einscheidung und Kompression von Nervenfasern durch Tumorgewebe wurde diskutiert [2,5].…”

Section: Introductionunclassified

Schmerzhaftes kutanes Leiomyosarkom

2006

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Leiomyosarcomas are derived from smooth muscles and only rarely involve the skin. A 73-year-old male presented with progressive tumor painful on the chest which had been present for 3 years and was tender to palpation, a finding more often associated with benign leiomyomas. immunohistochemical staining demonstrated multiple nerve fibers entrapped by atypical myofibrils, perhaps explaining the tenderness. Since 1996, we have excised five painless cutaneous leiomyosarcomas, in which entrapped nerves could not be demonstrated.

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Section: Introductionunclassified

Schmerzhaftes kutanes Leiomyosarkom

2006

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“…ECCRINE SPIRADENOMA, first described by Kersting and Helwig in 1956, is a benign uncommon neoplasm of the skin adnexa with a characteristic clinical and pathologic presentation 1 . Typically, an eccrine spiradenoma presents as a painful, slow‐growing, solitary nodule on the head or upper trunk 2 . Most lesions appear in adults between the second and fourth decades of life, without predilection for either gender 3 .…”

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confidence: 99%

“…1 Typically, an eccrine spiradenoma presents as a painful, slowgrowing, solitary nodule on the head or upper trunk. 2 Most lesions appear in adults between the second and fourth decades of life, without predilection for either gender. 3 Since the initial report characterizing eccrine spiradenoma in 1956, the literature has included other clinical presentations, including reports of multiple tumors and zosteriform/blaschkoid pattern spiradenomas.…”

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confidence: 99%

Familial Eccrine Spiradenoma: A Case Report and Review of the Literature

Poorten¹,

Barrett²,

Cook³

2003

Dermatol Surg

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Chronic Unilateral Eruption of Painful, Erythematous Papules and Nodules

Ramírez-Fort¹,

Doan²,

Nguyen³

et al. 2013

JAMA Dermatol

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A 72-year-old white woman of German heritage presented with a 30-year history of several painful lesions on the left side of her body. Clinical examination revealed numerous tender, erythematous papules and nodules over her left chest, flank, and lower extremity ( Figure 1). The patient's medical history was significant for hyperlipidemia, multiple uterine leiomyomas status after hysterectomy in 1972, and severe coronary artery disease status after coronary artery bypass grafting in 2004. The patient emigrated from Germany shortly after World War II; familial medical history was not available. Her medications were aspirin, warfarin, duloxetine, pregabalin, and atorvastatin. A shave biopsy was performed from a characteristic papule on the left lower extremity. Routine hematoxylin-eosin-stained sections are shown in Figure 2 and Figure 3.

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Painful Tumors of the Skin

Abstract: Our understanding of the mechanism of pain production by cutaneous tumors is limited by the small number of studies (and sample size) addressing the issue as well as by our incomplete general understanding of pain production.

Cited by 14 publications

References 33 publications

Schmerzhaftes kutanes Leiomyosarkom

Schmerzhaftes kutanes Leiomyosarkom

Familial Eccrine Spiradenoma: A Case Report and Review of the Literature

Chronic Unilateral Eruption of Painful, Erythematous Papules and Nodules

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