Painless giant cell thyroiditis diagnosed by fine needle aspiration and associated with intense thyroidal uptake of gallium

Sanders, Leonard R.; Moreno, Albert J.; Pittman, David L.; Jones, Jon C.; Spicer, Melvin J.; Tracy, Kevin P.

doi:10.1016/0002-9343(86)90647-9

Cited by 11 publications

(4 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…From a diagnostic standpoint, painless thyroidal destruction with definite inflammatory reactions is very difficult to distinguish from etiologies of other fevers of unknown origin such as infections, malignancy and collagen disease, which makes thorough systemic examinations necessary [12,23,24]. However, in our case and others [12,23], intense thyroid uptake of Ga-67 citrate provided the best evidence of the thyroid as the focus.…”

Section: Discussionmentioning

confidence: 65%

“…Furthermore, previous reports describing painless subacute thyroiditis [23,24], including two `outbreaks' of cases [30,31], do not fully explain the etiology for the condition, except for a report by de Bruin et al [31] in which the patient exhibited significantly lower frequency of HLA-B35 but increased frequency of HLA-B15 with painless subacute thyroiditis compared with the painful forms. From a diagnostic standpoint, painless thyroidal destruction with definite inflammatory reactions is very difficult to distinguish from etiologies of other fevers of unknown origin such as infections, malignancy and collagen disease, which makes thorough systemic examinations necessary [12,23,24]. However, in our case and others [12,23], intense thyroid uptake of Ga-67 citrate provided the best evidence of the thyroid as the focus.…”

Section: Discussionmentioning

confidence: 96%

“…Histopathologically, painless thyroiditis and painful lymphocytic thyroiditis are indistinguishable forms of lymphocytic thyroiditis (or Hashimoto's thyroiditis), whereas subacute thyroiditis is characterized by granulomatous and giant cell inflammation. Recently painless forms of subacute thyroiditis [23,24] and acute exacerbation of Hashimoto's thyroiditis [12] were reported. Histopathologically, the former showed classical granulomas with giant cell, while the latter showed typical Hashimoto's thyroiditis.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Painless Thyroiditis Associated with Severe Inflammatory Reactions in Amyloid Goiter: A Case Report.

et al. 2001

View full text Add to dashboard Cite

Abstract.We report the case of a 64-year-old woman with rheumatoid arthritis (RA) associated with high grade fever, malaise, and painless swelling of thyroid gland. Laboratory findings showed severe systemic inflammatory reactions, including increases in various cytokines such as IL-6. Gallium-67 citrate imaging revealed intense uptake in the painlessly enlarged thyroid gland. Histologically, biopsied specimens of thyroid showed diffuse amyloid infiltrations, which included amyloid A (AA) protein.Biopsies of rectum and stomach revealed similar amyloid depositions, indicating that the amyloid had a secondary origin, potentially due to RA. All clinical symptoms were relieved by intravenous pulsatile administration of methylprednisolone followed by oral prednisone, resulting in prolonged hypothyroid status. To our knowledge, this is the first case report in Japan describing painless thyroiditis with severe inflammatory reactions in amyloid goiter.

show abstract

Section: Discussionmentioning

confidence: 65%

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Painless Thyroiditis Associated with Severe Inflammatory Reactions in Amyloid Goiter: A Case Report.

et al. 2001

View full text Add to dashboard Cite

show abstract

“…This is not surprising, as it encompasses an overlap of traits similar to Hashimoto's thyroiditis, painless subacute thyroiditis, and Graves' disease (101). Clinically, patients experience symptoms of thyrotoxicosis with no or only mild enlargement of the thyroid and no infiltrative orbitopathy.…”

Section: High Uptake In Ectopic Sitesmentioning

confidence: 99%

Uncommon Causes of Thyrotoxicosis

Mittra¹,

Niederkohr²,

Rodríguez³

et al. 2008

J Nucl Med

View full text Add to dashboard Cite

Apart from the common causes of thyrotoxicosis, such as Graves' disease and functioning nodular goiters, there are more than 20 less common causes of elevated free thyroid hormones that produce the symptoms and signs of thyrotoxicosis. This review describes these rarer conditions and includes 14 illustrative patients. Thyrotropin and free thyroxine should be measured and, when the latter is normal, the free triiodothyronine level should be obtained. Measurement of the uptake of 123 I is recommended for most patients.

show abstract

Localized painful giant-cell thyroiditis without inflammatory signs in a euthyroid patient followed by serial sonography

Mizokami

Okamura

Sato

et al. 1998

J. Clin. Ultrasound

View full text Add to dashboard Cite

Painless giant cell thyroiditis diagnosed by fine needle aspiration and associated with intense thyroidal uptake of gallium

Cited by 11 publications

References 12 publications

Painless Thyroiditis Associated with Severe Inflammatory Reactions in Amyloid Goiter: A Case Report.

Painless Thyroiditis Associated with Severe Inflammatory Reactions in Amyloid Goiter: A Case Report.

Uncommon Causes of Thyrotoxicosis

Localized painful giant-cell thyroiditis without inflammatory signs in a euthyroid patient followed by serial sonography

Contact Info

Product

Resources

About