This study employs various Human-Computer Interaction methods to introduce an innovative system that empowers individuals with diverse abilities to use computers in novel ways. It combines gesture-based virtual mouse control and painting, along with eye and voice integration. Advanced eye-tracking technology to accurately detect and interpret ocular movements is incorporated. These movements are then mapped to specific on-screen actions, facilitated by the computer webcam. Simultaneously, hand gesture-based mouse control is also available, where it captures and analyzes intricate hand motions, translating them into precise on-screen commands. The hand tracking painting feature revolutionizes by providing users with a virtual canvas. Through hand movements, users can write and draw with ease with various tools, expanding the potential for interactive creativity. Easy switching between the traditional mouse, virtual mouse, and gesture-based painting modes are controlled by a voice assistant. This integration provides a comprehensive and adaptable digital environment, enhancing user convenience and mobility. This method seamlessly integrates of cutting-edge technologies, culminating in the creation of an inclusive and exceptionally intuitive user experience.