Although rivers are inherently dynamic systems that are susceptible to change, human impact on rivers in the last century is considered to have been so significant that it has caused an unprecedented intensity of geomorphological change in river channels and floodplains. As these changes often lead to deterioration of ecological conditions as well as increased flood risks, the approach to river management has changed over the past twenty years. There is an increasing emphasis on a holistic approach based on the understanding of river system processes, for which studies of geomorphological change in rivers represent a very important source of information. The aim of this review is to present the basic methods used in studies of geomorphological change in rivers, including the spatio-hierarchical delineation of the river system, data sources, and the most commonly analysed geomorphological characteristics and factors of change. The results of previous research are presented for the period of the last 150 years. The most important geomorphological changes include channel narrowing, incision, and reduction in the complexity of fluvial landforms and processes due to channelization and the construction of numerous barriers that disrupt the connectivity in water flow and sediment transport. Explaining the cumulative impacts and predicting future changes are the major research challenges. These challenges are related to the complexity of the river system, i.e. a large number of causal factors, connections, and interactions in the river system, and to the nonlinearity of the evolutionary trajectory of changes in rivers.