Palatability assessment of oral dosage forms for companion animals: A systematic review

Adenot, Charles C.; Abdelhakim, Hend E.

doi:10.1016/j.jddst.2022.103841

Cited by 3 publications

(3 citation statements)

References 26 publications

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“…Pleasant taste of the medication improves the ability to administer the drug according to 60.5% of cat owners and 46.7% of dog owners. Other studies from the UK described a better ability to enter liquids/pastes compared to tablets in cats [60,61]. In the present survey, tablets were found to be the preferred form of administration by dog and cat owners, followed by long-acting injections in cats and capsules in dogs, and in third position, solutions/suspensions/capsules in cats and long-acting injections in dogs.…”

Section: Discussionsupporting

confidence: 52%

Online-Assisted Survey on Antibiotic Use by Pet Owners in Dogs and Cats

Rocholl,

Zablotski,

Schulz

2024

Antibiotics

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The aim of the study was two-fold: first, to collect data on the use of antibiotics in Germany for dogs and cats and, second, their owners’ experiences and opinions. Using an anonymous online survey, dog and cat owners were asked about the last antibiotic administration in their pet. The inclusion criterion was any antibiotic administration within the last year. A total of 708 questionnaires from 463 dogs and 245 cats could be evaluated. Diarrhea was reported as the most common reason for antibiotic administration in dogs (18.4%). Wound infection/abscess/bite injury was the second most common reason in dogs (16.0%). In cats wound infection/abscess/bite injury was the most common reason (23.3%), followed by dental treatment (21.2%) and upper respiratory tract infections (16.7%). The most common antibiotics used systemically in both species were amoxicillin/clavulanic acid (32.5%), amoxicillin (14.8%), metronidazole (6.9%), and doxycycline (6.8%). While efficacy (99.9%) and tolerability (94.8%) were rated as most important for the choice of antibiotics, costs (51.6%) were cited as predominantly unimportant. First-line antibiotics were used significantly more often than critically important antibiotics. The majority of animal owners show awareness for avoidance of antibiotic resistance and the use of critically important antibiotics.

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Section: Discussionsupporting

confidence: 52%

Online-Assisted Survey on Antibiotic Use by Pet Owners in Dogs and Cats

Rocholl,

Zablotski,

Schulz

2024

Antibiotics

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“…First, an important premise for a successful baiting campaign is the availability of a bait that is well accepted (highly palatable) by the target species under field conditions (Gibson et al ., 2019 ). It is known that palatability is affected by several factors, such as physical aspect, taste and dosage form (Adenot and Abdelhakim, 2022 ). These factors are highly influenced by environmental exposure; in particular, rainfall, soil moisture, and temperature could play an important role in the longevity of baits (Allsop et al ., 2017 ).…”

Section: Discussionmentioning

confidence: 99%

“…Second, once the integrity of the bait was evaluated, their attractiveness and palatability over time were also assessed by preference testing (Thombre, 2004 ; Adenot and Abdelhakim, 2022 ) in order to find the best type of baits for the delivery on the field. Assessing the palatability of any proposed formulation on the target population prior to a baiting programme is an important step in predicting the effectiveness of that formulation for a particular population (Kappes et al ., 2022 ).…”

Section: Discussionmentioning

confidence: 99%

Baiting not-owned dogs against Echinococcus granulosus: innovative tools for integrated control

Ciccone,

Bosco,

Pepe

et al. 2024

Parasitology

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Cystic echinococcosis (CE), caused by the larval stage of the cestode Echinococcus granulosus, is one of the most widespread zoonoses in Mediterranean countries. Baiting not-owned dogs with praziquantel (PZQ), due to their key role in the maintaining the transmission of CE, currently appears to be the most effective way to limit the transmission of CE, as well as an important aspect to introduce for the control of this parasitic disease. Therefore, this study aims to test 3 types of PZQ-based baits by evaluating different parameters (integrity over time, attractiveness and palatability for dogs, and mechanical resistance after release to different altitudes) and the bait acceptance in field by target animals, i.e. not-owned dogs, by using camera traps. The double PZQ-laced baits (with a double layer of highly palatable chews) showed the greatest resistance in the environment while also preserving the attractiveness and palatability up to 10 days, also withstood heights of 25 m, thus resulting as the most suitable also for drone delivery. The results on the field showed that most of the baits were consumed by not-owned dogs (82.2%), while the remaining were consumed by wild boars (8.9%), foxes (6.7%), badgers (1.1%) and hedgehogs (1.1%), confirming the specific and high attractiveness of the double PZQ-laced baits for the target population and highlights how an anthelmintic baiting programme may be a viable tool for the management of E. granulosus among free-ranging dog populations in endemic rural areas.

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