Palatal mucormycosis masquerading as bacterial and fungal osteomyelitis: A rare case report

Rai, Shalu; Misra, Deepankar; Misra, Akansha; Jain, Ankit; Jain, Prasoon; Dhawan, Ayush

doi:10.4103/ccd.ccd_743_17

Cited by 14 publications

(20 citation statements)

References 9 publications

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“…Histopathologically, the differential diagnosis would be aspergillus and scedosporium, which shows branching at an acute angle and thinner septae. Polymerase chain reaction (PCR) can identify fungal DNA from the tissue samples and may improve the diagnostic ability [6,24].…”

Section: Discussionmentioning

confidence: 99%

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COVID-19 Coinfection With Mucormycosis in a Diabetic Patient

Roopa¹,

Thanthoni²,

Warrier³

2021

Cureus

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a form of β-Coronavirus of the Coronaviridae family, has been causing infection among humans worldwide leading to a pandemic emergency. New strains of SARS-CoV-2 have been evolving unceasingly, presenting with various systemic and oral manifestations. There has been an increase in the incidence of secondary infection in the coronavirus infected individual either due to pre-existing factors or the virus by itself is causing such infection, which is still unclear. As it is already known, immunocompromised and uncontrolled diabetic patients have an increased chance of developing mucormycosis. Herein, we report a case who presented with a swelling in the left cheek, eye, and avascular necrosis intraorally, post COVID-19 infection.

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Section: Discussionmentioning

confidence: 99%

“…Other therapies include adjunctive cytokines and iron chelation [25]. The mortality rate of mucormycosis varies from 16% to 100% with cutaneous form having 17%, rhino-cerebral form having 67%, pulmonary form having 83%, and gastrointestinal form having 100% [24].…”

Section: Discussionmentioning

confidence: 99%

COVID-19 Coinfection With Mucormycosis in a Diabetic Patient

Roopa¹,

Thanthoni²,

Warrier³

2021

Cureus

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“…Postdebridement defect if created can be rehabilitated by soft tissue and hard tissue reconstruction or by providing an obturator for the patients. [41]…”

Section: Discussionmentioning

confidence: 99%

Maxillary fungal osteomyelitis: A review of literature and report of a rare case

Srivastava

Mohpatra

Mahapatra

2019

Ann Maxillofac Surg

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Fungal osteomyelitis is a life-threatening and seldom seen opportunistic infection. It is commonly an affectation of the nose and paranasal sinuses within the orofacial region. It is an aggressive infection that needs to be addressed promptly to prevent fatal consequences. Here, we present a case of a 62-year-old female who presented with complaints of pain and pus discharge from the extraction socket of the left maxillary 23, 24, 25, 26 teeth. She had a history of uncontrolled diabetes mellitus. On further investigation, using diagnostic and Interventional aids, a final diagnosis of maxillary fungal osteomyelitis was made. The infective fungal agents were a mixture of Mucorales and Aspergillus species. A review of all literatures on the subject in the past 13 years using different search engines showed that craniofacial fungal infections with primary maxillary involvement are a rare phenomenon. The primary aim of reporting this case, therefore, is to highlight its rarity, presentation, management and most importantly the outcome of management.

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“…(5) Clinically the Rhino Cerebral Mucormycosis form usually presents as a paranasal infection with or without an extension into the oral cavity (44%-49%). (6) The Rhino Cerebral Mucormycosis is further subdivided into two subtypes: a highly fatal rhinoorbito-cerebral form which is invasive and may involve the ophthalmic and internal carotid arteries and a less fatal rhino-maxillary form which involves the sphenopalatine and greater palatine arteries, resulting in thrombosis of the turbinate and necrosis of the palate (7) Infections that extend from sinuses into the mouth produce painful, black necrotic ulcerations of the hard palate (the most common). Ulcers on gingiva, lip, and alveolar ridge have been reported.…”

confidence: 99%

Worth of Time Challenge and Multi Disciplinary Team in Rhino Maxillary Mucormycosis Mortality Detraction: Longitudinal Study in Al-Salam Teaching Hospital

Al-Rawee¹,

Al-Bakry²,

Khider³

et al. 2019

ATMPH

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BackgroundMucormycosis or Zygomycosis is a rapidly progressing fatal form of fungal infection mainly affecting the immunocompromised patients. The seriousness of such infection owing to its highly angioinvasion with high morbidity and mortality rate. At times, mucormycosis is considered as a diagnostic and therapeutic challenge to the clinicians. The multidisciplinary team (MDT) cooperation is of a substantial importance. ObjectivesFor highlighting the importance of early diagnosis of Mucormycosis in immunocompromised patients; especially diabetes, we have to draw attention to the role of MDT cooperation in reducing mortality and morbidity rate. Finally emphasize the role of maxillofacial surgeon in early diagnosis and surgical treatment too. Material and MethodsTen cases were recorded as mucormycosis infection with diabetes mellitus for a period from 2005 to 2012 in the maxillofacial unit, Al-Salam Teaching Hospital. Patients presented with sever swelling in the maxillary posterior region within a different time in seeking treatment. Inclusion Criteria: o Patients diagnosed as mucormycosis. o Patients are immunocompromised ( Diabetic )Particular dealing in management of cases after confirming attacks of mucormycosis processed including urgent amphotercine B (0.8mg/kg/day for 3 weeks) use, control the blood sugar level and surgical intervention. ResultAlthough urgent treatment started, two patients died because of the late presentation (20%). ConclusionThe key of management of this rapidly progressive fulminate disease is swift commencement of multidisciplinary treatments and early diagnosis.

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Palatal mucormycosis masquerading as bacterial and fungal osteomyelitis: A rare case report

Cited by 14 publications

References 9 publications

COVID-19 Coinfection With Mucormycosis in a Diabetic Patient

COVID-19 Coinfection With Mucormycosis in a Diabetic Patient

Maxillary fungal osteomyelitis: A review of literature and report of a rare case

Worth of Time Challenge and Multi Disciplinary Team in Rhino Maxillary Mucormycosis Mortality Detraction: Longitudinal Study in Al-Salam Teaching Hospital

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