Palladium‐Catalyzed Enantioselective Indole Allylic Alkylation with Chiral Phosphoramidite‐Selenide‐Based Ligands

Feng, Bin; Zhang, Yun‐Fan; Li, Shan; You, Ge‐Yun; Xuan, Jun

doi:10.1002/ejoc.202300861

Eur J Org Chem

2023

DOI: 10.1002/ejoc.202300861

|View full text |Cite

Palladium‐Catalyzed Enantioselective Indole Allylic Alkylation with Chiral Phosphoramidite‐Selenide‐Based Ligands

Bin Feng,

Yun‐Fan Zhang,

Shan Li

et al.

Abstract: The Pd/phosphoramidite‐selenide‐catalyzed highly enantioselective C‐3 allylic alkylation with a wide range of indole nucleophiles have been developed, giving the corresponding products with up to 95% yield and 99% ee.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 85 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Metal complexes with selenium-based ligands in organic synthesis

Mamgain,

Kostić,

Divac

et al. 2024

RUSS CHEM REV

View full text Add to dashboard Cite

Designing ligands is a crucial and significant element in homogeneous catalysis. Over the past two decades, a range of compounds with selenium substitutions have been employed as scaffolds for ligands in the development of transition metal catalytic systems. Air and moisture stability, good solubility in different solvents, stability toward oxidation and excellent electron-donating properties of selenium atom are some of the key features of organoselenium compounds that make them suitable candidates for application as ligands. The metal complexes of selenium ligands are widely acknowledged for their ability to catalyze diverse organic reactions, including but not limited to the Sonogashira coupling reaction, Heck coupling reaction, Suzuki-Miyaura coupling reaction, imidazole arylation, transfer hydrogenation reaction, oxidation of alcohols, and ortho-arylation of phenols. In certain instances, there has been notable observation of exceptionally high catalytic efficiency. Additionally, catalysis often enables a broad substrate range in numerous scenarios, as it is tolerant towards different functional groups. This review highlights the key synthetic methods employed in the design of recent instances of organoselenium compounds as ligands for synthesizing transition metal complexes. Additionally, it explores their utilization in various preparative organic transformations.<br> The bibliography includes 133 references.

show abstract

Metal complexes with selenium-based ligands in organic synthesis

Mamgain,

Kostić,

Divac

et al. 2024

RUSS CHEM REV

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Palladium‐Catalyzed Enantioselective Indole Allylic Alkylation with Chiral Phosphoramidite‐Selenide‐Based Ligands

Abstract: The Pd/phosphoramidite‐selenide‐catalyzed highly enantioselective C‐3 allylic alkylation with a wide range of indole nucleophiles have been developed, giving the corresponding products with up to 95% yield and 99% ee.

Cited by 1 publication

References 85 publications

Metal complexes with selenium-based ligands in organic synthesis

Metal complexes with selenium-based ligands in organic synthesis

Contact Info

Product

Resources

About