Palladium-Catalyzed α-Arylation of Ketones

Asymmetric Construction of Quaternary Carbon Stereocenter by Pd-Catalyzed Intramolecular .ALPHA.-Arylation

“…In summary, we have found the use of H 8 -BINAP as a ligand, compared with carbene ligand 1, improved reaction conversions in an enantioselective intramolecular a-arylation [16][17][18][19][20] …”

Recent Advances in C—H Functionalizations Assisted by Removable and/or Modifiable Directing Groups

“…此外, 该小组还实现了钯催化 的苯乙醇羟基诱导的 C-H 键羰基化/酯化串联反应, 一 步高效地构建了 1-异色酮类化合物 [56] . 1997 年 , Buchwald [74] , Hartwig [75] , Satoh [ …”

Utilizing Mor‐DalPhos/Palladium‐Catalyzed Monoarylation in the Multicomponent One‐Pot Synthesis of Indoles

“…[13][14][15][16][17][18][19][20][21] Encouraged by these observations, we envisioned that these two classes of transformations (Buchwald-Hartwig amination [22][23][24][25][26] and ketone monoa-arylation [27][28][29][30] ) could be combined in the development of a new and synthetically useful one-pot, multicomponent indole synthesis starting from commercially available ortho-dihaloarenes, alkyl ketones, and primary amines; one possible reaction sequence of this type is outlined in Scheme 1. Scheme 1.…”