Palladium-promoted benzothiophene condensation in NS₂ligands

Abstract

The reaction of 2,6-bis(o-methoxycarbonylphenylthiomethyl)pyridine with PdCI2 or Ru(Me2SO)6( BF& in methanol produces a tridentate non-symmetrical ligand incorporating the benzothiophene fragment.

Novel Tetranuclear Orthometalated Complexes of Pd(II) and Pt(II) Derived from p-Isopropylbenzaldehyde Thiosemicarbazone with Cytotoxic Activity in cis-DDP Resistant Tumor Cell Lines. Interaction of These Complexes with DNA

“…The two five-member chelate rings involving the metallic atom are almost coplanar. The Pd−Pd distances (Pd(1)−Pd(2) = 3.341(3) Å and Pd(3)−Pd(4) = 3.330(2) Å) and the Pt−Pt distances (Pt(1)−Pt(2) = 3.3218(4) Å and Pt(3)−Pt(4)= 3.3205(4) Å) indicate no direct bond between the metallic atoms, but a very weak interaction can be postulated in agreement with the reported values for polynuclear complexes with Pd or Pt, a Pd 4 core (2.549(2)−3.539(1) Å) and 2.537(1)-3.507(1) Å platinum complexes . A similar ring disposition has been described in palladium complexes with amido and in palladium and platinum complexes with 2-(1-naphthyl)benzothiazoline as ligands.…”

Synthesis of Pyridine NS2 Ligands Incorporating 1-Methoxycarbonyl-2-thio(o-carborane). Are They a Route to “Carboranethiophene” Compounds?

“…Recent studies in our group were focused to the synthesis of new ligands incorporating the NS 2 (pyridinedithia) coordinating unit. Interest in such coordinating systems stems in their potential as sensitizers in ion selective electrodes, as carriers in supported liquid membranes and in the interesting reactivity with metals, e.g., benzothiophene condensations promoted by Pd(II) and Pt(II) for appropriate NS 2 ligands, as 2,6-bis(2‘-methoxycarbonylphenylthiomethyl)pyridine, represented in Figure . On the other hand, carboranyl compounds have found applications as electrolytes for nonaqueous solvents or in solvent extraction of radionuclides .…”

Coordination of the nido‐carboranyldiphosphine ligand to ruthenium(II): the first example of the tricoordinating capacity of the 7,8‐(PPh2)2‐7,8‐C2B9H10 moiety

“…The ratio of the two species was estimated by the integrated intensity of the peaks in the 1 H{ 11 B} NMR spectrum. Method I yields 64% of 2a and 37% of 2b, whereas 40% of 2a and 60% of 2b are achieved using 8,9,25 The signal at −1.81 ppm is a tetraplet ( 1 J BH = 106 Hz) and the others are broad signals. When the 1 H{ 11 B} NMR spectrum was recorded, the broad resonances at −3.27 and −6.55 ppm were shown to be doublets due to coupling to 31 The 1 H{ 11 B} and 31 P{ 1 H} resonances (see Fig.…”

“…5), similar to the structure reported for [RuCl(7,8-µ-7,8-(SCH 2 -CH 2 S)-7,8-C 2 B 9 H 10 ) 2 ]. 9 When a 2 : 1 ratio is used the orange solid 4 is obtained. The 11 B{ 1 H} NMR spectrum of this solid shows ill-defined resonances that overlap in the region 0 to −20 ppm integrating 14B and two bands at −31.9 (2B) and −37.8 ppm (2B).…”