Palliative care interventions for people with multiple sclerosis

Effect of Short-term Integrated Palliative Care on Patient-Reported Outcomes Among Patients Severely Affected With Long-term Neurological Conditions

“…There is a lack of robust evidence to support service and policy developments that improve palliative care provision for people with LTNCs. 11 , 12 To date, there are 3 published small-scale pilot or phase 2 randomized clinical trials of palliative care interventions in neurological conditions. 13 , 14 , 15 Findings of these trials reported slight improvements in symptom burden without harmful effects; however, they reported inconsistent effects on other outcomes (eg, QoL, caregiver burden).…”

Physicians’ Conceptions of the Dying Patient: Scoping Review and Qualitative Content Analysis of the United Kingdom Medical Literature

“…There was no standard, consistent meaning of palliative care (Bausewein & Higginson, 2012) but it was generally described as an approach to increasing quality of life of patients and their families (Allsop et al, 2018). Howell et al (2015) described palliative care as part of a transition from active treatments, others that it is compatible with active treatments (Puckey & Bush, 2011), or that palliative care itself is active (Latorraca et al, 2019).…”

EAN guideline on palliative care of people with severe, progressive multiple sclerosis

“…64 It should be noted, however, that in this systematic review pain and sleeping problems were considered as PC adverse events and the pre-specified secondary outcome measures included relapse-free survival, progression-free survival, neuropsychological assessment and the EDSS. 64 The other study was a pragmatic RCT from the UK, which demonstrated that a standing frame programme significantly increased motor function in people with severe MS and was cost-effective in comparison to standard care. 65 The limited evidence on PC in MS (and in other neurological conditions) contrasts with the situation in oncology.…”