2015
DOI: 10.1177/107327481502200409
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Palliative Sedation in Patients with Cancer

Abstract: Proportionate palliative sedation is used to manage and relieve refractory symptoms in patients with cancer during their last days or hours of life. Evidence suggests that its use has no detrimental effect on survival. A different decision-making process is used to manage the withdrawal of hydration than the process used to determine whether proportionate palliative sedation is appropriate. Communication between patients, their relatives, and the health care staff is important during this medical intervention.

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Cited by 30 publications
(25 citation statements)
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“…The prevalence of PS varies considerably worldwide (1–88%), mainly because of differences in PS definitions, care settings and in clinical practice patterns. Mixed cases in similar settings, the degree of adherence to PS guidelines and the level of expertise of health care professionals may also play a role for this wide range [ 8 10 ].…”
Section: Introductionmentioning
confidence: 99%
“…The prevalence of PS varies considerably worldwide (1–88%), mainly because of differences in PS definitions, care settings and in clinical practice patterns. Mixed cases in similar settings, the degree of adherence to PS guidelines and the level of expertise of health care professionals may also play a role for this wide range [ 8 10 ].…”
Section: Introductionmentioning
confidence: 99%
“…Despite recent advances in palliative medicine, sedating a terminally ill patient is regarded as an indispensable treatment to manage refractory symptoms such as severe agitated delirium or asphyxial dyspnoea and to relieve intractable distress [13]. Palliative sedation can be used for a short period (intermittent sedation) or continuously until death and its depth varies from a lower level of consciousness to unconsciousness.…”
Section: Introductionmentioning
confidence: 99%
“…Palliative sedation can be used for a short period (intermittent sedation) or continuously until death and its depth varies from a lower level of consciousness to unconsciousness. These various characteristics partly explain the wide-ranging prevalence of this last resort treatment reported in the literature (1–88%) [1]; and the practice may in fact be under-reported [3]. The biomedical and ethical aspects of palliative sedation are nevertheless widely debated [48] and best practice guidelines have been adopted [9–15].…”
Section: Introductionmentioning
confidence: 99%
“…More precise, and potentially reversible, deep palliative sedation with benzodiazepines, the modern practice, was obviously not an option in those times. Palliative sedation does not have a detrimental effect on survival …”
Section: Discussionmentioning
confidence: 99%
“…Palliative sedation does not have a detrimental effect on survival. 13 Schur's choice of dosage warrants consideration because parenteral opioid administered to such a naïve patient would not be acceptable modern practice. Undoubtedly, the doses of morphine were considerable (and unwise), whether they were 20 or 30 mg.…”
Section: Discussionmentioning
confidence: 99%