Palliative therapy in pancreatic cancer—interventional treatment with stents

Abstract

Interventional treatment with stents in pancreatic cancer is a topic that developed during recent years and new fields of palliative stent therapy have evolved. The increasing life expectancy of patients with unresectable pancreatic cancer increases the need for clinical and cost effective therapeutic interventions. Current literature, guidelines, practice and evidence were reviewed. Besides the most obvious biliary stenting via endoscopic retrograde cholangiopancreatography (ERCP), pancreatic and gastroduodenal stenting as well as percutaneous transhepatic cholangiography (PTC) and the rapidly growing field of endosonographic stent implantation in the palliative care of patients with pancreatic cancer are being discussed from several points of view in this review.

Gaps and Opportunities in the Diagnosis and Treatment of Pancreatic Cancer

“…However, adverse events, such as duodenal perforation, bleeding, transient cholangitis, stent obstruction, kinking, spontaneous dislodgement, food impaction, may occur. Further studies are needed to determine newer technical innovation in the design and delivery system, improving LAMS performance by increase the duration of patency and reduction of adverse effects during deployment [146][147][148].…”

Modified hepaticocholecystoenterostomy technique for certain hepatobiliary and pancreatic diseases: case series report by a single surgeon

“…[7][8][9] Although the patients with stents had a shorter hospital stay, the cost of therapy was higher than that in the open surgery group for biliary-enteric anastomosis. [10][11][12] In some situations, the assessment of the actual stage of the disease is limited, and radical surgery is impossible. Therefore, the method of biliary-enteric anastomosis is a suitable choice.…”