Palmar cutaneous metastasis from carcinoma cervix

Elamurugan, T P; Agrawal, Ajit; Ravikumar, Dinesh; Aravind, Ramraj Jayabalan; Naskar, Dipankar; Kate, Vikram; Reddy, Rani; Elamurugan, Sujindra; Siddaraju,; Basu, Debdatta; Parthasarathy,

doi:10.4103/0378-6323.77486

Cited by 7 publications

(3 citation statements)

References 7 publications

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“…This case, however, is distinctive for several reasons. First, in prior reports of cutaneous metastases from cervical squamous cell carcinoma, the grossly visible nodules are usually single or a small cluster of multiple papules [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] . In our patient's case, the cutaneous metastases were innumerable and located diffusely over the anterior abdominal wall, vulva, perineum, and bilateral proximal lower extremities (see Figure 1).…”

Section: Discussionmentioning

confidence: 99%

“…This clinical scenario is even less common in literature originating from the United States, due to the lower overall incidence of cervical cancer [3][4][5] . Case reports have documented various sites of cutaneous metastases, including the face and neck [6] , scalp [7][8][9] , vulva [5,[10][11] , upper and lower extremities [12][13] , umbilicus (Sister Mary Joseph nodule) [14] , trunk/abdominal wall [3][4][5]15] , and surgical incision/drain sites [16][17] . Prior authors have found that the occurrence of metastases to the skin generally implies terminal disease, with the average survival following diagnosis ranging from 3-6 months, even in cases where palliative chemo-and radiotherapy are administered [15] .…”

Section: Introductionmentioning

confidence: 99%

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Cutaneous metastases from cervical squamous cell carcinoma in a 55 year-old woman: a rarely reported manifestation

McCarthy

Laucirica

2014

CRCP

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Squamous cell carcinoma of the cervix was once the most common gynecologic cancer in the world, accounting for significant morbidity and mortality. With the advent of routine Papanicolaou screening in the United States during the latter half of the twentieth century, cervical cancer now accounts for a much smaller proportion of cancer deaths. Despite the advances that have been made in screening and early detection, women of low socio-economic status and immigrants from other countries who may not have access to health care continue to present with high-stage disease. Manifestations of advanced disease include direct invasion of structures adjacent to the cervix and distant metastases to the lung, bone, and liver. In approximately 0.5-1 percent of cases, metastases to the skin and soft tissue occur, most commonly to the abdominal wall and vulva, followed less frequently by the perineum and extremities. This particular manifestation has come to be regarded as a sign of terminal disease, with most patients surviving 3-6 months despite chemotherapy. Clinically, this may not be a diagnosis that is anticipated by the pathologist examining the biopsy. We present the case of a 55 year-old woman with a history of untreated squamous cell carcinoma of the cervix who presented with rapidly spreading, painful erythematous papules of the vulva, lower anterior abdominal wall, and proximal lower extremities. This case highlights a rare presentation of metastatic squamous cell carcinoma of the cervix, and underscores the importance of obtaining adequate clinical history, investigating a wide range of diagnoses as part of the differential diagnosis, and distinguishing primary cutaneous squamous cell carcinoma from a metastasis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Cutaneous metastases from cervical squamous cell carcinoma in a 55 year-old woman: a rarely reported manifestation

McCarthy

Laucirica

2014

CRCP

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“…Cutaneous metastasis in the palmar area from visceral cancer has been reported in only four cases in the English-language literature13-16 since Camiel et al originally reported skin metastasis on palm and sole from lung cancer. However, this had not yet been reported in the Korean-language literature.…”

Section: Discussionmentioning

confidence: 99%

Metastatic Gastric Adenocarcinoma Presenting as a Solitary Plaque on the Palm

et al. 2011

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Cutaneous metastases from gastric adenocarcinoma are extremely rare. When present, metastasis typically signifies disseminated disease with a poor prognosis. We report a case of an 80-year-old male with gastric cancer who presented with a single, erythematous plaque on the left palm, a very rare site for skin metastasis. Results of a skin biopsy demonstrated that the cutaneous metastasis originated from the stomach. This report emphasized the need for appropriate investigation into newly appearing, unusual, or persistent skin lesions.

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