Palmar fasciitis and polyarthritis syndrome is multicausal

Fernández‐Nebro, Antonio; Fernández-Ruiz, Alexia; Rodríguez, M.; Haro, M de; Rodríguez-Andreu, J; González-Santos, Pedro

doi:10.1007/bf02231700

Cited by 8 publications

(5 citation statements)

References 7 publications

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“…A patient treated with perlindol for depression developed a similar condition, but this was much more inflammatory in nature with clear uptake on bone scanning and complete resolution after drug withdrawal and moderate-dose prednisolone. 40 Palmar fasciitis and polyarthritis syndrome has also been described in association with anti-tuberculous therapy 41 and with a benign ovarian cyst. 39 The pathogenesis of this condition is unknown.…”

Section: Discussionmentioning

confidence: 98%

Palmar fasciitis and polyarthritis syndrome associated with transitional cell carcinoma of the bladder

Clarke

Kennedy

Hollingworth

2011

Journal of the American Academy of Dermatology

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Section: Discussionmentioning

confidence: 98%

Palmar fasciitis and polyarthritis syndrome associated with transitional cell carcinoma of the bladder

Clarke

Kennedy

Hollingworth

2011

Journal of the American Academy of Dermatology

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“…4 Although often associated with malignancy, non-neoplastic presentations of PFPA have been described. 5,6 Non-paraneoplastic PFPA syndrome has been seen in association with tuberculosis, thyroid disease, benign ovarian cyst and as an isolated finding. 6 In paraneoplastic cases the most frequent associated malignancy is ovarian cancer, 4 but other tumours reported include gastric cancer, 7 colonic carcinoma, 7 pancreatic carcinoma, 8 nonsmall cell lung cancer, 9 breast cancer, 10 tubal carcinoma, 11 cervical carcinoma 3 and prostate cancer.…”

Section: Discussionmentioning

confidence: 98%

Indurated reticulate palmar erythema as a sign of paraneoplastic palmar fasciitis and polyarthritis syndrome

2009

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A 62-year-old woman presented with a 6-month history of polyarthritis. She had also noted a 2-month history of indurated palmar erythema and increasing bilateral hand swelling and stiffness. A biopsy from the area of palmar erythema showed interstitial fibroplasia within the dermis and subcutis representing a palmar fibromatosis. This presentation appears to belong to the spectrum of palmar fasciitis and polyarthritis syndrome. Rheumatologists have recognised this syndrome as a paraneoplastic disorder and subsequent investigations in our patient revealed an elevated cancer antigen 125 and an inoperable ovarian carcinoma. Indurated palmar erythema is a sign that is not widely recognised by dermatologists as a clue for this paraneoplastic syndrome, and skin biopsy demonstrating dermal and subcutaneous fibroplasia may help in diagnosis in the absence of advanced signs of palmar fasciitis.

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“…PFPA has been implicated also with ovarian non-malignant tumors including endometrial cyst (1) and paraovarian cyst (22). As PFPA was suspected, a more complete investigation was performed in these 2 cases.…”

Section: Ovarian Benign Tumorsmentioning

confidence: 99%

Palmar fasciitis with polyarthritis-associated ovarian cancer: Case report and literature review

et al. 2017

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Abstract. Palmar fasciitis and polyarthritis (PFPA) is an uncommon disorder clinically characterized by rapidly developing bilateral arthritis of the hands and fasciitis of the palms. This cancer-associated syndrome, primarily linked to ovarian cancer, has also been associated with multiple different malignancies. PFPA symptoms usually precede the detection of ovarian cancer. In all patients from case series and single case reports described, ovarian cancer is already present at an advanced stage. Therefore, the authors aimed to present a case and systematically review available evidence on the association between PFPA and ovarian cancer, as gynecological oncologists. Awareness and recognition of PFPA may allow for earlier diagnosis and treatment of an occult ovarian cancer. The commitment of the attending gynecologists to become familiar with and identify rare diseases may lead to the detection at an early and curative stage and potentially life-saving therapeutic interventions.

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Palmar fasciitis and polyarthritis syndrome is multicausal

Cited by 8 publications

References 7 publications

Palmar fasciitis and polyarthritis syndrome associated with transitional cell carcinoma of the bladder

Palmar fasciitis and polyarthritis syndrome associated with transitional cell carcinoma of the bladder

Indurated reticulate palmar erythema as a sign of paraneoplastic palmar fasciitis and polyarthritis syndrome

Palmar fasciitis with polyarthritis-associated ovarian cancer: Case report and literature review

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