Palpable purpura, gingival ulcerations and joint pain in a 24‐year‐old man

Illes, Monica; Luttosch, F.; Pierer, Matthias; Simon, Jan C.; Ziemer, Mirjana

doi:10.1111/j.1610-0387.2012.07981.x

Cited by 1 publication

(1 citation statement)

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“…A Medline, Web of Science, EMBASE, and ScienceDirect search was performed with 235 articles (Figure 1 ). A total of 31 case reports were included (Ah‐See et al, 1996 ; Allen et al, 1991 ; Aravena et al, 2014 ; Barrett et al, 2011 ; Bergé et al, 2000 Bhatt & Hall, 2009 ; Carter & Brizman, 2008 ; Cohen et al, 1990 ; Dhalkari et al, 2020; Eufinger et al, 1992 ; Fonseca et al, 2017 ; Genuis & Pewarchuk, 2014 ; Handlers et al, 1985 ; Hanisch et al, 2016 ; Heera et al, 2012 ; Hernández et al, 2008 ; Illes et al, 2012 ; Israelson et al, 1981 ; Kertesz et al, 2021 ; Lilly et al, 1998 ; Lustmann et al, 1994 ; Msallem et al, 2019 ; Napier et al, 1993 ; Patrick & Altman, 2019 ; Reboll‐Ferrer et al, 2010 ; Ruokonen et al, 2009 ; Siar et al, 2011 ; Sung et al, 2015 ; Thompson et al, 2018 ; Xing et al, 2011 ). Four case series (Allen et al, 1991 ; Nico et al, 2020 ; Patten and Tomecki, 1993 ; Stewart et al, 2007 ) and one prospective study (Szczeklik et al, 2019 ) were included in the analysis with an aggregate level of evidence 3b.…”

Section: Resultsmentioning

confidence: 99%

Oral granulomatosis with polyangiitis a systematic review

Labrador

Valdez²,

Marín

et al. 2023

Clinical & Exp Dental Res

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Objective: Granulomatosis with polyangiitis is an unusual multisystemic inflammatory disease, with vasculitis of small-and medium-sized vessels, with a predilection for upper lower airways and kidneys. The etiology remains unknown although it may originate from different stimuli, in genetically susceptible patients.Materials and Methods: A detailed database search was performed. The variables were demographics, localization, histopathological findings, antineutrophil cytoplasmic autoantibody, cytoplasmic (c-ANCA) tests, treatment, and follow-up.Results: Fifty-two cases were identified; the mean age was 49.6 years, with a range from 6 to 87 years. It was most frequently seen in females (57.7%). The most common race was white (59.6%). The most frequent location was in the maxillary gingiva (28.8%), followed by both the upper and lower gingiva (19.2%). The most common clinical presentation was "strawberry gingivitis" (61.5%). The main symptom was pain, in 50%.Regarding the c-ANCA test, it was positive in 71.2% of cases. The most common therapy was prednisone and cyclophosphamide, utilized in 51.9%. The average follow-up was 23.6 months, and 88.5% of patients were still alive at follow-up. Conclusion:The diagnosis initially was difficult to establish, an early diagnosis and treatment are mandatory. If untreated the disease can be associated with morbidity and mortality. For the oral clinician, this disease needs to be addressed in the differential diagnosis of oral lesions.

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