2022
DOI: 10.3389/fmicb.2022.1011578
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Pan-genomic analysis of Corynebacterium amycolatum gives insights into molecular mechanisms underpinning the transition to a pathogenic phenotype

Abstract: Corynebacterium amycolatum is a nonlipophilic coryneform which is increasingly being recognized as a relevant human and animal pathogen showing multidrug resistance to commonly used antibiotics. However, little is known about the molecular mechanisms involved in transition from colonization to the MDR invasive phenotype in clinical isolates. In this study, we performed a comprehensive pan-genomic analysis of C. amycolatum, including 26 isolates from different countries. We obtained the novel genome sequences o… Show more

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Cited by 4 publications
(1 citation statement)
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“…It has been isolated from blood cultures, cellulitis, wounds, endocarditis, and peritonitis (250,253). A recent pangenomic study of drug resistant and commensal isolates of C. amycolatum gave insight into the core genome and the transition from commensal to pathogenic phenotype (262).…”
Section: Amycolatummentioning
confidence: 99%
“…It has been isolated from blood cultures, cellulitis, wounds, endocarditis, and peritonitis (250,253). A recent pangenomic study of drug resistant and commensal isolates of C. amycolatum gave insight into the core genome and the transition from commensal to pathogenic phenotype (262).…”
Section: Amycolatummentioning
confidence: 99%