Pancreatic Colloid Carcinoma Presenting with Acute Pancreatitis

Abstract

Pancreatic colloid carcinoma, also known as mucinous non-cystic carcinoma, is a rare subtype of pancreatic cancer accounting for 1%-3% of the pancreatic malignant neoplasms. We herein report a woman who initially presented for acute pancreatitis. Computed tomography showed pancreatic swelling due to acute pancreatitis and a 16-mm mass with an enhanced margin in the pancreatic tail. We performed endoscopic ultrasound fine-needle aspiration. The patient was diagnosed with pancreatic colloid carcinoma, and distal pancreatectomy was performed. This case indicates that pancreatic colloid carcinoma should be considered as a differential diagnosis of pancreatic tumor presenting with acute pancreatitis.

Gum, Sap and Canker-Colloid Carcinoma-Pancreas

“…Articulated mucin lakes frequently demonstrate incomplete layering with neoplastic epithelial cells. Besides, mucin secreted by tumour cells may be retained during histological processing (Fujii M, Okamoto Y, Fujioka SI et al, 2022;Orcutt ST, Coppola D, Hodul PJ., 2016).…”

“…Upon ultrastructural examination, mucigen granules appear disseminated upon the stromal surface. A distinctive basement membrane circumscribing glandular articulations or neoplastic aggregates is absent (Fujii M, Okamoto Y, Fujioka SI et al, 2022;Orcutt ST, Coppola D, Hodul PJ., 2016). Grading of colloid carcinoma pancreas contingent to microscopic evaluation is denominated as…”

“…Adoption of diagnostic manoeuvers as an incisional biopsy may contribute to emergence of complications as thromboembolic phenomenon. Exceptionally, colloid carcinoma pancreas delineates complications such as pseudomyxoma peritonei (Yasuoka H, Kato H, Asano Y et al, 2022;Fujii M, Okamoto Y, Fujioka SI et al, 2022).…”

“…Grossly, colloid carcinoma pancreas emerges as an enlarged, well demarcated tumefaction with a mean tumour diameter of 5 centimetres. Cut surface is solid, firm and gelatinous (Yasuoka H, Kato H, Asano Y et al, 2022;Fujii M, Okamoto Y, Fujioka SI et al, 2022). Cytological smears of the abundantly mucoid colloid carcinoma pancreas may be challenging to disperse upon glass slides.…”

“…Cytological smears of the abundantly mucoid colloid carcinoma pancreas may be challenging to disperse upon glass slides. Besides, malignant component may delineate minimal cellularity (Yasuoka H, Kato H, Asano Y et al, 2022;Fujii M, Okamoto Y, Fujioka SI et al, 2022).…”